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The potential of albuminuria as a biomarker of diabetic complications
Diabetes mellitus is a disease of dysregulated blood glucose homeostasis. The current pandemic of diabetes is a significant driver of patient morbidity and mortality, as well as a major challenge to healthcare systems worldwide.
Maxwell, Alexander P.; id_orcid +5 more
core +1 more source
Estimated pulse wave velocity and albuminuria in chronic renal disease patients
Background: In chronic kidney disease (CKD) increased pulse wave velocity is associated with renal micro-vascular damage and burdened prognosis in this population of patients.
Vaia D. Raikou +2 more
doaj +1 more source
Objective: To evaluate the contribution of non-traditional risk factors to coronary heart disease (CHD) incidence in Indigenous adults. Design, setting and participants: Cohort study of 1706 Aboriginal and Torres Strait Islander adults from 26 remote ...
Li, Ming +2 more
core +1 more source
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain +11 more
doaj +1 more source
Capillary Rarefaction Associates with Albuminuria: The Maastricht Study [PDF]
Albuminuria may be a biomarker of generalized (i.e., microvascular and macrovascular) endothelial dysfunction. According to this concept, endothelial dysfunction of the renal microcirculation causes albuminuria by increasing glomerular capillary wall ...
Schram, Miranda T. +35 more
core +2 more sources
A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND. [PDF]
Although albuminuria and subsequent advanced stage chronic kidney disease are common among patients with diabetes, the rate of increase in albuminuria varies among patients.
Dov Shiffman +7 more
doaj +1 more source
Activin A, a cytokine belonging to the transforming growth factor-β family, has been shown to play pivotal roles in tissue remodeling after renal injury and is present in elevated levels in diabetic patients.
Shih-Chen Chang +8 more
doaj +1 more source
Albuminuria and heart failure: is it an albuminuria or the hypertension? [PDF]
Ingelsson et al. 1 elegantly emphasized albuminuria as a risk factor for heart failure in elderly hypertensive men and present thought-provoking speculative mechanisms. However, the association between albuminuria and heart failure was seen in untreated hypertensive men compared to treated hypertension, suggesting that treated hypertensive men had ...
openaire +1 more source

