Results 81 to 90 of about 87,895 (325)

Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]

, 2015
Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E, Divers, Jasmin, Freedman, Barry I, Hawfield, Amret T, Kaysen, George A, Kimmel, Paul L, Langefeld, Carl D, Pajewski, Nicholas M, Raj, Dominic S, Reboussin, David M, Ricardo, Ana C, Rocco, Michael V, Sedor, John R, Systolic Blood Pressure Intervention Trial (SPRINT), Wright, Jackson T   +14 more
core   +1 more source

Clinical Outcomes and Treatment Strategies of Adult Transplant‐Associated Thrombotic Microangiopathy: External Validation of Harmonizing Definitions and High‐Risk Criteria

American Journal of Hematology, EarlyView.
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina, Meera Sridharan, Ronald S. Go, Ann M. Moyer, Nelson Leung, Maria Alice V. Willrich, Robert Wolf, Rabee Kassis, Almothana Manasrah, Mira A. Kohorst, Urshila Durani, Aasiya Matin, Mehrdad Hefazi, Saad J. Kenderian, Abhishek A. Mangaonkar, Mithun V. Shah, Mark R. Litzow, William J. Hogan, David Dingli, Hassan B. Alkhateeb   +19 more
wiley   +1 more source

Multiparametric renal magnetic resonance imaging: A reproducibility study in renal allografts with stable function

NMR in Biomedicine, Volume 36, Issue 2, February 2023., 2023
Reproducibility of a multiparametric MRI protocol including Pseudo‐Continuous Arterial Spin Labeling (PCASL), intravoxel incoherent motion (IVIM), and T1 mapping sequences was assessed, and normal values of the measured parameters were characterized in renal transplant patients with stable function.
Rebeca Echeverria‐Chasco, Paloma L. Martin‐Moreno, Nuria Garcia‐Fernandez, Marta Vidorreta, Verónica Aramendia‐Vidaurreta, David Cano, Arantxa Villanueva, Gorka Bastarrika, Maria A. Fernández‐Seara   +8 more
wiley   +1 more source

TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice

Disease Models & Mechanisms, 2016
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain, Bhavya Khullar, Neelam Oswal, Balaji Banoth, Prashant Joshi, Balachandran Ravindran, Subrat Panda, Soumen Basak, Anna George, Satyajit Rath, Vineeta Bal, Shailaja Sopory   +11 more
doaj   +1 more source

The association between serum activin A levels and albuminuria among community-dwelling middle-aged and older adults in Taiwan

Scientific Reports, 2021
Activin A, a cytokine belonging to the transforming growth factor-β family, has been shown to play pivotal roles in tissue remodeling after renal injury and is present in elevated levels in diabetic patients.
Shih-Chen Chang, Chien-Yi Hsu, Li-Kuo Liu, Ya-Wen Lu, Yi-Lin Tsai, Ruey-Hsing Chou, Po-Hsun Huang, Liang-Kung Chen, Shing-Jong Lin   +8 more
doaj   +1 more source

KAJIAN EKSPRESI TGF-ββββ1, MMP-9, KOLAGEN TIPE-1, KOLAGEN TIPE-IV, GLOMERULOSKLEROSIS, INTERSTISIAL FIBROSIS, ALBUMINURIA PADA KEJADIAN NEFROTOKSIK DOXORUBICIN DAN NEFROPROTEKTIF PENTOXIFYLLIN DENGAN HEWAN COBA MENCIT GALUR SWISS JANTAN [PDF]

, 2010
Pemakaian Doxorubicin (DXR) dalam pengobatan kanker semakin meningkat, dengan meningkatnya morbiditas kanker. Efek nefrotoksik dari DXR masih menjadi masalah.
Purwanto, Bambang
core   +1 more source

Effect of vitamin D supplementation on blood pressure:a systematic review and meta-analysis incorporating individual patient data [PDF]

, 2015
D-PRESSURE Collaboration: et al.[Importance]: Low levels of vitamin D are associated with elevated blood pressure (BP) and future cardiovascular events.
Alvarez, Jessica, Beveridge, Louise A., Boxer, Rebecca, Dalbeni, Andrea, Gepner, Adam D., Isbel, Nicole M., Jorde, Rolf, Khan, Faisel, Larsen, Thomas, Macdonald, Helen M., Nagpal, Jitender, Petchey, William G., Scragg, Robert, Stricker, Hans, Stroebel, Franziska, Struthers, Allan D., Tangpricha, Vin, Toxqui, Laura, Vaquero, M. Pilar, Wamberg, Louise, Witham, Miles D., Zittermann, Armin   +21 more
core   +3 more sources

Albuminuria and heart failure: is it an albuminuria or the hypertension? [PDF]

European Heart Journal, 2007
Ingelsson et al. 1 elegantly emphasized albuminuria as a risk factor for heart failure in elderly hypertensive men and present thought-provoking speculative mechanisms. However, the association between albuminuria and heart failure was seen in untreated hypertensive men compared to treated hypertension, suggesting that treated hypertensive men had ...
openaire   +2 more sources

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

Animal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang, Salma Althobaiti, Braeden Pinkerton, Xin Fu, Zhenshan Jia, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang   +8 more
wiley   +1 more source

Fibrosis imaging with multiparametric proton and sodium MRI in pig injury models

NMR in Biomedicine, Volume 36, Issue 2, February 2023., 2023
Multiparametric MRI can predict intrarenal fibrosis. ADC cortex, ΔR2*, ΔT1, the 23Na medulla/cortex ratio, and plasma creatinine resulted in the most robust model for intrarenal fibrosis prediction. Abstract Chronic kidney disease (CKD) is common and has huge implications for health and mortality.
Camilla W. Rasmussen, Nikolaj Bøgh, Sabrina K. Bech, Thomas H. Thorsen, Esben S. S. Hansen, Lotte B. Bertelsen, Christoffer Laustsen   +6 more
wiley   +1 more source