Improving equity in Alzheimer's disease research: Biomarker disclosure in underserved populations [PDF]
Abstract Background The early diagnosis of Alzheimer's disease (AD) demands reliable biomarkers and accessible detection methods. Evidence shows that combining brain imaging with cerebrospinal fluid (CSF) biomarkers significantly enhances the sensitivity and specificity of AD diagnosis.
Oviedo D +12 more
europepmc +2 more sources
The influence of APOEε4 on cognition in Hispanics: The Panama Aging Research Initiative ‐ Health Disparities Study [PDF]
Abstract Background The apolipoprotein E (APOE) gene is a well‐established risk factor for Alzheimer's disease. This study aims to investigate the relationship between APOE genotype and cognitive aging in a sample of Hispanics. We also present data from the research protocol of an ongoing clinical study within the PARI‐HD program. The main objective is
Villarreal A +37 more
europepmc +2 more sources
Effects of a non‐pharmacological program combining physical and cognitive interventions in older adults in Panama [PDF]
Abstract Background Currently, pharmacological interventions to delay cognitive decline in older adults have proven to be insufficient. Non‐pharmacological approaches, however, are gaining attention for improving cognition, enhancing well‐being, and alleviating caregiver burden.
Quiros E +13 more
europepmc +2 more sources
The Assessment of Knowledge, or Whether We Possess Knowledge or Twofold Ignorance about Our Place in the Universe [PDF]
The article aims to investigate the notion and foundation of the concept of knowledge to assess our place in the Universe via understanding of ourselves.
Pavlo Sodomora, Svitlana Yahelo
doaj +1 more source
Experiences in the use of multiple doses of convalescent plasma in critically ill patients with COVID-19: An early phase 1 descriptive study. [PDF]
Abstract Background At the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic, transfusion of coronavirus disease 2019 (COVID‐19) convalescent plasma (CCP) emerged as a potential therapeutic strategy to help patients severely afflicted by COVID‐19.
Aguilar R +20 more
europepmc +2 more sources
DISAGREEMENT AND KNOWLEDGE: THE CASE OF PLATO’S ALCIBIADES [PDF]
If there is widespread disagreement in an intellectual community, are its members in some sense failing epistemically? In this paper, I will offer a reconstruction of the first sustained attempt to answer this question.
Toomas Lott
doaj +1 more source
Psicología Política en el Alcibiades I de Platón
Este ensayo propone una lectura del diálogo platónico Alcibíades I. En el texto, vemos a Sócrates como joven maestro aproximándose al también joven Alcibíades, quien sabemos se convertirá en un prominente y hubristico gobernante de la Atenas democrática
José Daniel Parra
doaj +1 more source
ALCIBIADES Alcibiades [...] (Zweiter Theil) ([I]) [...] (Vierter Theil) ([1 ...
Meißner, August Gottlieb
core +4 more sources
Corrupting the Youth: Xenophon and Plato on Socrates and Alcibiades
Socrates’ students, who are attracted by the philosophic life, offer starkly different portraits of Alcibiades, the most illustrious among Socrates’ students who chose a political life. Their presentations diverge particularly
Gregory A. McBrayer
doaj +1 more source
Alzheimer diseases CSF biomarkers correlate with systemic biomarkers in a cohort of Hispanics [PDF]
Abstract Background We are conducting a biomarker‐based study to describe the demographic and biomarker profiles of Panamanians. The objective of this report is to present the main findings on CSF, genetic and serological biomarkers’ distribution and their association with cognition in a cohort of elderly people in Panama.
Villarreal A +13 more
europepmc +2 more sources

