Results 131 to 140 of about 2,727,544 (257)

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

open access: yesBritish Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read   +4 more
wiley   +1 more source

Advancing essential services and research on fetal alcohol spectrum disorders [PDF]

open access: yes
"In 2004, the National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect, coordinated by the Centers for Disease Control and Prevention's National Center on Birth Defects and Developmental Disabilities, established a working group committed ...

core  

Health and wellbeing outcomes for defendants entering the Alcohol-MERIT program [PDF]

open access: yes, 2014
Aim: To assess whether the NSW Alcohol-MERIT program improves the health and wellbeing of defendants. Method: Before their participation in the Alcohol-MERIT program, the health and wellbeing of 123 defendants was measured using the SF-36, Kessler-10 ...
Lily Trimboli   +2 more
core  

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

Fetal alcohol spectrum disorders: current issues in awareness, prevention and intervention [PDF]

open access: yes, 2014
This paper reviews the research and current policy surrounding prenatal alcohol exposure and fetal alcohol spectrum disorders (FASD). Alcohol use during pregnancy is linked to a spectrum of adverse fetal outcomes.
Sara McLean, Stewart McDougall
core  

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Reasons for relapse in patients with alcohol dependence

open access: yesArchives of Mental Health, 2012
Background: Alcoholism is a chronic relapsing disorder. Alcohol dependence is characterized by a prolonged course of alcohol-related problems and a persistent vulnerability to relapse. Even though there is an improvement in multiple domains of life after
Anupama Korlakunta   +2 more
doaj  

An all‐in‐one fucosylated gold nanocluster probe enables NIR‐II imaging and multi‐mechanistic therapy of acute kidney injury

open access: yesBMEMat, EarlyView.
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang   +7 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

Psychiatric Emergency Presentations in Detained Adolescents: A Comparison With Community‐Living Adolescents

open access: yesCriminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Adolescents involved in the juvenile justice system have high rates of psychiatric disorder and social vulnerability. Those in custodial or semi‐custodial detention may be particularly vulnerable to psychiatric emergencies, but the clinical factors associated with these crises remain insufficiently understood.
Maria Carolina Lobato Machado   +7 more
wiley   +1 more source

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