Results 11 to 20 of about 2,117 (125)

Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study

European Neuropsychopharmacology, 2021
Sodium oxybate (SMO) has been approved in Italy and Austria for the maintenance of abstinence in alcohol dependent (AD) patients. Although SMO is well tolerated in AD patients, cases of abuse and misuse have been reported outside the therapeutic setting.
Guiraud J., Addolorato G., Aubin H. -J., Batel P., de Bejczy A., Caputo F., Goudriaan A. E., Gual A., Lesch O., Maremmani I., Perney P., Poulnais R., Raffaillac Q., Soderpalm B., Spanagel R., Walter H., van den Brink W.   +16 more
openaire   +6 more sources

Investigating Whether Bereavement by Suicide and Other Unnatural Causes Has a Deterrent Effect on Alcohol or Drug Use in Young Adults

International Journal of Environmental Research and Public Health, 2022
Bereavement by suicide and other unnatural causes is associated with suicide but evidence regarding risk of substance misuse is inconsistent. This may be due to heterogeneity in patterns of alcohol or drug use after traumatic bereavement; some increasing use to cope with the loss and others reducing use.
Alexandra Pitman, Fiona Stevenson, David Osborn   +2 more
openaire   +3 more sources

Assessment of Alcohol-Induced Dose Dumping with a Hydrocodone Bitartrate Extended-Release Tablet Formulated with CIMA® Abuse Deterrence Technology [PDF]

Clinical Drug Investigation, 2015
Greater drug content requirements for extended-release (ER) opioids necessitate greater protection against dose dumping. Hydrocodone ER employs the CIMA(®) Abuse-Deterrence Technology platform, which provides resistance against rapid release of the active moiety when the tablet is manipulated or taken with alcohol.Assess effects of alcohol on ...
Darwish, Mona, Bond, Mary, Yang, Ronghua, Tracewell, William, Robertson, Philmore   +4 more
openaire   +2 more sources

Past behaviours and future intentions: An examination of perceptual deterrence and alcohol consumption upon a range of drink driving events

Accident Analysis & Prevention, 2020
The threat of application of legal sanctions remains the prominent approach to reduce the prevalence of drink driving in a vast array of motoring jurisdictions. However, ongoing questions remain regarding: (a) the extent that such mechanisms impact upon offending behaviours, (b) the deleterious effect alcohol consumption has on decisions to drink and ...
Freeman, J, Parkes, A, Lewis, N, Davey, JD, Armstrong, KA, Truelove, V   +5 more
openaire   +3 more sources

Repurposing the alcohol-deterrent drug Disulfiram for the radiotherapy of glioblastoma using an in vitro model of fractionated γ-radiation

, 2020
Glioblastoma (GB) is the most common primary brain tumor in adults. It is also one of the most lethal and devastating malignancy with a median patient survival of 14 months despite surgical resection and radiochemotherapy. Recent data has suggested that radiotherapy may trigger treatment resistance by promoting the diffuse invasive phenotype of GB ...
openaire   +1 more source

Examining the Impact of Trial Length on Detecting Medication Effects for Alcohol Use Disorder: A Meta-Regression Study. [PDF]

Alcohol Clin Exp Res (Hoboken)
Belnap MA, Witkiewitz K, Schacht JP, Anton RF, Aldridge AP, Nieto SJ, Ray LA.   +6 more
europepmc   +1 more source

Medication Availability for Alcohol Use Disorder in Substance Use Disorder Treatment Facilities. [PDF]

JAMA Netw Open
Mizushima Y, Cantor J, McBain RK, Zhang F, Burnett A, Dong E, Kofner A, Breslau J, Stein BD, Yu H.   +9 more
europepmc   +1 more source

Surgical health policy advocacy and suicide prevention: the San Diego-Coronado bridge case. [PDF]

Inj Epidemiol
Austin JR, Song JH, Haines LN, Berndtson AE, Weaver JL, Santorelli JE, Lee JG, Kobayashi LM, Adams LM, Smith A, Doucet JJ, Liepert AE.   +11 more
europepmc   +1 more source

Self-Poisoning With Ibuprofen in Youth: A What, When and Why Clinical Framework. [PDF]

Clin Med Insights Pediatr
Dehestani B, Kelly L, McNicholas F.
europepmc   +1 more source

Alcohol Consumption, Deterrence and Crime in New York City

, 2013
Hope Corman, Naci Mocan
openaire   +1 more source