Results 91 to 100 of about 623,469 (364)

Controlled drinking, harm reduction and their roles in the response to alcohol-related problems [PDF]

, 2006
This article first distinguishes three meanings of the term ‘harm reduction’ in the literature on alcohol problems: a European sense in which a change in drinking is not necessarily required; an American sense which includes the controlled drinking (CD ...
Heather, Nick
core   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Heavy Drinking in University Students With and Without Attention-Deficit/Hyperactivity Disorder: Contributions of Drinking Motives and Protective Behavioral Strategies

Substance Abuse: Research and Treatment, 2017
This study examined rates of heavy drinking and alcohol problems in relation to drinking motives and protective behavioral strategies in university students with a documented current diagnosis of attention-deficit/hyperactivity disorder (ADHD; n = 31 ...
Andrea L Howard, Tyler R Pritchard
doaj   +1 more source

Liver transplantation for alcoholic liver disease: a retrospective analysis of recidivism, survival and risk factors predisposing to alcohol relapse [PDF]

, 2013
Background and study aims : Alcoholic liver disease (ALD) is the second most common indication for liver transplantation. The aim of this study was to evaluate the alcohol relapse rate and long-term survival after liver transplantation for ALD and to ...
Berrevoet, Frederik, Colle, Isabelle, de Hemptinne, Bernard, Deruytter, Elise, Geerts, Anja, Rogiers, Xavier, Trepo, Eric, Troisi, Roberto, Van Steenkiste, Christophe, Van Vlierberghe, Hans   +9 more
core  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Cotton Recruits Soil‐Derived Delftia tsuruhatensis to Suppress Aphid Detoxification Via Salicylic Acid‐Mediated Defense

Advanced Science, EarlyView.
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue, Fengchao Diao, Qiqing Yu, Xiangzhen Zhu, Tingfang Zhong, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Junyu Luo, Jinjie Cui, Xueke Gao   +11 more
wiley   +1 more source

Scoping review of assessment tools for, magnitudes of and factors associated with problem drinking in population-based studies

BMJ Open
Background The term “problem drinking” includes a spectrum of alcohol problems ranging from excessive or heavy drinking to alcohol use disorder. Problem drinking is a leading risk factor for death and disability globally.
Bronwyn Myers, Solomon Teferra, Awoke Mihretu, Kefyalew Dagne   +3 more
doaj   +1 more source

Pleasure, profit and pain: Alcohol in New Zealand and the contemporary culture of intoxication [PDF]

, 2013
This book details the rich, complex and often contested role of alcohol in New Zealand society. It explores the three fundamental alcohol rights that continue to fight for dominance of the national drinking culture: the rights of individual drinkers to ...
Campbell, Maxine M., Lyons, Antonia, McEwan, Brett James, Swain, David   +3 more
core   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source