Results 121 to 130 of about 1,830,234 (387)

Scoping review of assessment tools for, magnitudes of and factors associated with problem drinking in population-based studies

BMJ Open
Background The term “problem drinking” includes a spectrum of alcohol problems ranging from excessive or heavy drinking to alcohol use disorder. Problem drinking is a leading risk factor for death and disability globally.
Bronwyn Myers, Solomon Teferra, Awoke Mihretu, Kefyalew Dagne   +3 more
doaj   +1 more source

ALDH2*2 and peer drinking in East Asian college students [PDF]

, 2017
Background: The ALDH2*2 allele (A-allele) at rs671 is more commonly carried by Asians and is associated with alcohol-related flushing, a strong adverse reaction to alcohol that is protective against drinking.
Chartier, Karen G., Dick, Danielle M., Kendler, Kenneth S., O\u27Shea, Taryl, Thomas, Nathaniel, Webb, Bradley Todd   +5 more
core   +2 more sources

Chronic Nicotine Activates Stress/Reward-Related Brain Regions and Facilitates the Transition to Compulsive Alcohol Drinking

Journal of Neuroscience, 2015
Alcohol and nicotine are the two most co-abused drugs in the world. Previous studies have shown that nicotine can increase alcohol drinking in nondependent rats, yet it is unknown whether nicotine facilitates the transition to alcohol dependence.
R. M. Leão, F. Cruz, L. Vendruscolo, G. de Guglielmo, M. Logrip, C. Planeta, B. Hope, G. Koob, O. George   +8 more
semanticscholar   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Consumption of salted meat and its interactions with alcohol drinking and tobacco smoking on esophageal squamous‐cell carcinoma

International Journal of Cancer, 2015
Etiology of esophageal cancer has not yet been clearly documented, especially in high‐risk regions. To evaluate the association between salted meat intake and esophageal squamous‐cell carcinoma (ESCC) and to explore its joint effects with alcohol ...
Sihao Lin, Xiaorong Wang, Chengyu Huang, Xudong Liu, Jin Zhao, I. Yu, D. Christiani   +6 more
semanticscholar   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Identification and characterization of dysregulated P-element induced wimpy testis-interacting RNAs in head and neck squamous cell carcinoma. [PDF]

, 2019
It is clear that alcohol consumption is a major risk factor in the pathogenesis of head and neck squamous cell carcinoma (HNSCC); however, the molecular mechanism underlying the pathogenesis of alcohol-associated HNSCC remains poorly understood.
Ku, Jonjei, Kuo, Selena Z, Li, Pin Xue, Ongkeko, Weg M, Saad, Maarouf A, Wang-Rodriguez, Jessica, Yu, Michael Andrew, Zheng, Hao   +7 more
core  

Maternal Gestational Smoking, Diabetes, Alcohol Drinking, Pre-Pregnancy Obesity and the Risk of Cryptorchidism: A Systematic Review and Meta-Analysis of Observational Studies

PLoS ONE, 2015
Background Maternal gestational smoking, diabetes, alcohol drinking, and pre-pregnancy obesity are thought to increase the risk of cryptorchidism in newborn males, but the evidence is inconsistent.
Lin Zhang, Xinghuan Wang, Xin-min Zheng, Tong-Zu Liu, Wei-Bin Zhang, Hang Zheng, Mi Chen   +6 more
semanticscholar   +1 more source

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

Advanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua, Ning Ding, Yiming Hua, Xiaoke Wang, Yu Xu, Xiangrui Qiao, Xue Shi, Ting Bai, Ying Xiong, Xiaozhen Zhuo, Chong Fan, Juan Zhou, Yue Wu, Junhui Liu, Zuyi Yuan, Ting Li   +15 more
wiley   +1 more source

“Fourteen Dollars for One Beer!” Pre‐drinking is associated with high‐risk drinking among Victorian young adults

Australian and New Zealand Journal of Public Health, 2013
Objective: Pre‐drinking entails consuming alcohol before attending licensed venues. We examined the relationship between pre‐drinking, intention to get drunk and high‐risk drinking among Victorians aged 18–24 years, to consider whether reducing pre ...
Sarah MacLean, Sarah Callinan
doaj   +1 more source