Results 131 to 140 of about 1,830,234 (387)

Youth Alcohol Access, Consumption, and Consequences in Anchorage, Alaska: 2012 Update [PDF]

open access: yes, 2012
Updates prior report, Youth Alcohol Access, Consumption, and Consequences in Anchorage, Alaska: Identification of Indicators by Marny Rivera and Jennifer McMullen. Report prepared for the Volunteers of America CMCA Project.
McMullen, Jennifer   +2 more
core  

Changes in undergraduate student alcohol consumption as they progress through university [PDF]

open access: yes, 2008
BACKGROUND: Unhealthy alcohol use amongst university students is a major public health concern. Although previous studies suggest a raised level of consumption amongst the UK student population there is little consistent information available about ...
AM Roche   +48 more
core   +4 more sources

Alcohol alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice.

open access: yesAlcoholism: Clinical and Experimental Research, 2015
BACKGROUND Binge alcohol drinking is a particularly risky pattern of alcohol consumption that often precedes alcohol dependence and addiction. The transition from binge alcohol drinking to alcohol addiction likely involves mechanisms of synaptic ...
Abigail E. Agoglia   +5 more
semanticscholar   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen   +18 more
wiley   +1 more source

In vino veritas: Theory and evidence on social drinking [PDF]

open access: yes
It is a persistent phenomenon in many societies that a large proportion of alcohol consumption takes place in company of other people. While the phenomenon of social or public drinking is well discussed in disciplines as social psychology and ...
Frank, Björn   +2 more
core  

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen   +11 more
wiley   +1 more source

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

open access: yesAdvanced Science, EarlyView.
Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li   +14 more
wiley   +1 more source

New Zealand culture of intoxication: Local and global influences [PDF]

open access: yes, 2010
This article shows that attitudes towards and behaviours involving the consumption of alcohol in New Zealand have long been problematic. It provides an historical account of social, economic and legislative factors which have influenced the development ...
Campbell, Maxine M.   +2 more
core   +1 more source

Contribution of Time of Drinking Onset and Family History of Alcohol Problems in Alcohol and Drug Use Behaviors in Argentinean College Students [PDF]

open access: yes, 2013
Aims: The aim of the study was to analyze independent and potential interactive effects of age at drinking onset and family history of alcohol abuse on subsequent patterns of alcohol drinking, alcohol-related problems and substance use.
Caneto, Florencia   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy