Results 41 to 50 of about 603,663 (315)

Nucleus Accumbens Shell and mPFC but not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking

Frontiers in Neuroscience, 2016
Addiction to alcohol remains a major social and economic problem, in part because of the high motivation for alcohol that humans exhibit and the hazardous binge intake this promotes.
Kelly Lei, Scott Wegner, JiHwan Yu, Arisa Mototake, Bing Hu, Frederic Hopf   +5 more
doaj   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Alcohol consumption in young adults: the role of multisensory imagery. [PDF]

, 2013
Accepted 19.11.2013Little is known about the subjective experience of alcohol desire and craving in young people. Descriptions of alcohol urges continue to be extensively used in the everyday lexicon of young, non-dependent drinkers. Elaborated Intrusion
Andrade, J, Connor, JP, Drennan, J, Feeney, GFX, Fry, M-L, Gullo, MJ, Kavanagh, DJ, May, J, Previte, J, Tjondronegoro, D, White, AM   +10 more
core   +1 more source

#BingeDrinking—Using Social Media to Understand College Binge Drinking: Qualitative Study

JMIR Human Factors, 2022
BackgroundHazardous drinking among college students persists, despite ongoing university alcohol education and alcohol intervention programs.
Madison N Cirillo, Jennifer P Halbert, Jessica Gomez Smith, Nour Sami Alamiri, Karen S Ingersoll   +4 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Effect of State Coalitions to Reduce Underage Drinking: A National Evaluation [PDF]

, 2006
Summarizes an evaluation of how the RWJF-funded Reducing Underage Drinking Through Coalitions Project to reduce youth drinking changed media coverage of alcohol-related issues, state policy, youth drinking behaviors, and alcohol-related driving ...
Alexander Wagenaar, Deanna Lewis
core  

The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. [PDF]

, 2015
Distinct environmental and conditioned stimuli influencing ethanol-associated appetitive and consummatory behaviors may jointly contribute to alcohol addiction.
Belin, David, Bullmore, Edward T., Economidou, Daina, Everitt, Barry J., Garc?a-Pardo, Maria P., Giuliano, Chiara, Goodlett, Charles R., Robbins, Trevor W.   +7 more
core   +5 more sources

Genome-wide association studies of the self-rating of effects of ethanol (SRE). [PDF]

, 2020
The level of response (LR) to alcohol as measured with the Self-Report of the Effects of Alcohol Retrospective Questionnaire (SRE) evaluates the number of standard drinks usually required for up to four effects. The need for a higher number of drinks for
Agrawal, Arpana, Dick, Danielle, Edenberg, Howard J, Farris, Sean, Foroud, Tatiana, Goate, Alison, Goldman, David, Hesselbrock, Victor, Johnson, Emma C, Joslyn, Geoff, Kapoor, Manav, Kramer, John, Lai, Dongbing, Liu, Yunlong, Mayfield, R Dayne, McCutcheon, Vivia V, Nurnberger, John, Porjesz, Bernice, Ramchandani, Vijay A, Rao, Xi, Schuckit, Marc, Schwandt, Melanie, Tischfield, Jay, Wetherill, Leah   +23 more
core   +2 more sources

A novel human laboratory alcohol self-administration paradigm for medication screening: Modeling the ability to resist drinking and heavy drinking

Drug and Alcohol Dependence Reports, 2022
Background: Human laboratory analogues of drinking behavior provide an efficient, cost-effective mechanistic evaluation of a medication signal on drinking.
Sherry A. McKee, Terril L. Verplaetse
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source