Results 71 to 80 of about 2,622,964 (299)

Personal Correlates of Support for Medical and Recreational Cannabis Legalization in Australia

open access: yesFrontiers in Psychiatry, 2021
Introduction and Aims: Increasingly more Australians are in favor of legalizing medical and recreational cannabis use. This paper explored the personal characteristics of those who supported each of these policies in Australia.Design: Cross-sectional ...
Vivian Chiu   +10 more
doaj   +1 more source

Prevalence of Alcohol Consumption and Hazardous Drinking, Tobacco and Drug use in urban Tanzania, and Their associated Risk Factors. [PDF]

open access: yes, 2009
Evidence suggests substance abuse in Tanzania is a growing public health problem. A random sample of 899 adults aged 15-59 in two urban sites of differing levels of poverty surveyed alcohol, tobacco and illicit substance use.
Joseph Mbatia   +47 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Pheniramine dependence: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Pheniramine (AvilTM)is an antihistaminic drug, which also has anti-cholinergic properties. It is used to treat allergic conditions such as hay fever and urticaria.
Rabia Bilici   +2 more
doaj  

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Voluntary temporary abstinence from alcohol during “Dry January” and subsequent alcohol use [PDF]

open access: yes, 2015
Objective: Temporary abstinence from alcohol may convey physiological benefits and enhance well-being. The aim of this study was to address a lack of information about: (1) correlates of successful completion of a planned period of abstinence, and (2 ...
Bond, Rod   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Associations between childbirth, gang exposure and substance use among young women in Cape Town, South Africa

open access: yesSubstance Abuse Treatment, Prevention, and Policy
The prevalence and influence of gangs on adolescents and young adults remain a concern in Western Cape, South Africa—particularly as they have one of the largest gang presence.
Felicia A. Browne   +4 more
doaj   +1 more source

The Young Women’s Health CoOp in Cape Town, South Africa: Study protocol for a cluster-randomised trial for adolescent women at risk for HIV

open access: yesBMC Public Health, 2018
Background South Africa remains the global epicentre of HIV infection, and adolescent women have the highest incidence of HIV in the country. South Africa also has high rates of alcohol and other drug (AOD) use, violence, and gender inequality.
Wendee M. Wechsberg   +9 more
doaj   +1 more source

Unhealthy Alcohol Use [PDF]

open access: yesJAMA, 2021
Avani K, Patel, Alëna A, Balasanova
openaire   +2 more sources

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