Results 71 to 80 of about 60,359,659 (310)

Drinking to Cope During COVID-19 Pandemic: The Role of External and Internal Factors in Coping Motive Pathways to Alcohol Use, Solitary Drinking, and Alcohol Problems.

Alcoholism: Clinical and Experimental Research, 2020
BACKGROUND The COVID-19 pandemic has resulted in massive disruptions to society, to the economy, and to daily life. Some people may turn to alcohol to cope with stress during the pandemic, which may put them at risk for heavy drinking and alcohol-related
Jeffrey D. Wardell, T. Kempe, Karli K. Rapinda, Alanna Single, Elena Bilevicius, Jona R. Frohlich, C. Hendershot, M. Keough   +7 more
semanticscholar   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Patterns of alcohol use in adolescents: early predictors and adulthood outcomes.

, 2020
Alcohol is one of the leading risk factors for death and disability in young people . Although people usually first start drinking alcohol at around 15-16 years of age, this can vary, and adolescents often follow different patterns or “trajectories” of ...
Yuen, Wing See
core  

Protocol for a national monthly survey of alcohol use in England with 6-month follow-up: 'the Alcohol Toolkit Study'. [PDF]

, 2015
BACKGROUND: Timely tracking of national patterns of alcohol consumption is needed to inform and evaluate strategies and policies aimed at reducing alcohol-related harm.
Brennan, A, Acton, C., Brennan, Alan, Holmes, J, Holmes, John, Drummond, Colin, Lock, Karen, Lock, K, West, R, Drummond, Colin; id_orcid, Hickman, Matthew, West, R., Hickman, M., Lock, K., Beard, E., Hickman, M, Beard, E, Brown, J., Kaner, Eileen, Kaner, E, Brennan, A., Kaner, E., Michie, S, Michie, Susan, Drummond, C., Acton, C, Walmsley, M., West, Robert, Walmsley, M, Beard, Emma, Brown, Jamie, Holmes, J., Acton, Crispin, Drummond, C, Michie, S., Brown, J, Walmsley, Matthew   +36 more
core   +1 more source

Developing a tablet computer-based application (‘App’) to measure self-reported alcohol consumption in Indigenous Australians

BMC Medical Informatics and Decision Making, 2018
Background The challenges of assessing alcohol consumption can be greater in Indigenous communities where there may be culturally distinct approaches to communication, sharing of drinking containers and episodic patterns of drinking. This paper discusses
KS Kylie Lee, Scott Wilson, Jimmy Perry, Robin Room, Sarah Callinan, Robert Assan, Noel Hayman, Tanya Chikritzhs, Dennis Gray, Edward Wilkes, Peter Jack, Katherine M. Conigrave   +11 more
doaj   +1 more source

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review

Journal of the American Medical Association (JAMA), 2018
Importance Alcohol consumption is associated with 88 000 US deaths annually. Although routine screening for heavy alcohol use can identify patients with alcohol use disorder (AUD) and has been recommended, only 1 in 6 US adults report ever having been ...
H. Kranzler, M. Soyka
semanticscholar   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Alcohol use and dementia: a systematic scoping review

Alzheimer's Research & Therapy, 2019
Alcohol use has been identified as a risk factor for dementia and cognitive decline. However, some patterns of drinking have been associated with beneficial effects.
J. Rehm, O. Hasan, S. Black, K. Shield, M. Schwarzinger   +4 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Patterns of alcohol policy enforcement activities among local law enforcement agencies: A latent class analysis

, 2015
Aims: We assessed levels and patterns of alcohol policy enforcement activities among U.S. local law enforcement agencies. Design/Setting/Participants: We conducted a cross-sectional survey of a representative sample of 1,631 local law enforcement ...
Jones-Webb, Rhonda, Rutledge, Patricia C., Nelson, Toben F., Erickson, Darin J., Lenk, Kathleen M., Toomey, Traci L.   +5 more
core   +1 more source