Results 191 to 200 of about 306,000 (257)

The effect of alcohol withdrawal therapy on gut microbiota in alcohol use disorder and its link to inflammation and craving. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
Proskynitopoulos PJ   +11 more
europepmc   +1 more source

Effective acetalization of furfural catalyzed by Fe‐ and Co‐oxalates: impact of alcohols structure on products composition

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Fe‐, Co‐, and FeCo‐oxalates supported on silica gel (5 wt% metal load) were synthesized, characterized, and tested for the first time in solvent‐free furfural (FF) acetalization with C1–C8 alcohols at 70–170 °C under both conventional and microwave (MW)‐assisted conditions. The interaction of FF with linear C1–C4 alcohols yielded pincer‐shaped
Alexander Pokutsa   +3 more
wiley   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Hospital-Wide Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal.

open access: yesJAMA Netw Open
Wolpaw BJ   +9 more
europepmc   +1 more source

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