Results 151 to 160 of about 413,633 (296)

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Intestinal Microbiotas and Alcoholic Hepatitis: Pathogenesis and Therapeutic Value. [PDF]

Int J Mol Sci, 2023
Zheng J, Li Z, Xu H.
europepmc   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

Journal of Clinical Ultrasound, EarlyView.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio, Maria Angelica Jungles Malikoski, Eduardo Henrique Bonotto, Sandra Monica Tochetto, Marco Stephan Lofrano‐Alves   +4 more
wiley   +1 more source

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis. [PDF]

Elife, 2023
Ahmadi AR, Song G, Gao T, Ma J, Han X, Hu MW, Cameron AM, Wesson RN, Philosophe B, Ottmann S, King E, Gurakar A, Qi L, Peiffer B, Burdick J, Anders R, Zhou Z, Lu H, Feng D, Chen CS, Qian J, Gao B, Zhu H, Sun Z.   +23 more
europepmc   +1 more source

2020 National viral hepatitis progress report [PDF]

The National Viral Hepatitis Progress Report provides information on ten data indicators, providing an objective way to assess progress toward achieving key viral hepatitis goals.Publication date from document properties.NationalProgressReport2020 ...

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Perinatal predictors of parenting stress trajectories during the first 3 years of parenthood: A Maternal and Child Health Handbook cohort study

JCPP Advances, EarlyView.
Abstract Background Evidence of how parenting stress evolves during early childhood is limited. We aimed to identify parenting stress trajectories involving children aged 1 month to 3 years, and to determine their perinatal predictors. Methods Data were obtained from 3133 mothers in the Tokyo Teen Cohort (TTC), a population‐based cohort of children ...
Nao Oikawa, Mariko Hosozawa, Syudo Yamasaki, Shuntaro Ando, Mitsuhiro Miyashita, Kaori Baba, Junko Niimura, Naomi Nakajima, Satoshi Yamaguchi, Yuko Morimoto, Sho Kanata, Hiroyasu Iso, Mariko Hiraiwa‐Hasegawa, Kiyoto Kasai, Atsushi Nishida   +14 more
wiley   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Hepatitis B questions and answers for health professionals [PDF]

Overview and Statistics -- Transmission, Symptoms, and Treatment -- Hepatitis B Vaccination ...

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Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva‐Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe‐Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba   +10 more
wiley   +1 more source

Alcohol and hepatic regeneration

Gastroenterology, 1980
W, Frank, P R, Holt
openaire   +2 more sources