Results 231 to 240 of about 113,555 (294)

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, EarlyView.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source

Substance Use and Sex Index version 2 (SUSI‐2): Validation of a brief questionnaire for the measurement of behaviours associated with transmission of blood borne viruses and sexually transmitted infections

Addiction, EarlyView.
Abstract Aims This study sought to validate a community‐acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood‐borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual ...
Brendan Clifford, Raimondo Bruno, Liam Acheson, Michael E. Cecilio, Krista J. Siefried, Jack Freestone, Vincent J. Cornelisse, Brendan Crozier, Nicky Bath, Nadine Ezard   +9 more
wiley   +1 more source

A cost–benefit analysis of the implementation and scale‐up of harm reduction interventions in the Australian Capital Territory

Addiction, EarlyView.
Abstract Background and aims Harm reduction interventions aim to reduce negative consequences of drug use. We aimed to estimate the cost, health impact and economic benefits of current, expanded and new harm reduction interventions for people who use drugs in the Australian Capital Territory.
Anna L. Bowring, Tom Tidhar, Anna Olsen, Christopher Bailie, Kelvin Burke, Rowan Martin‐Hughes, Helen Keane, Paul Dietze, Nick Scott   +8 more
wiley   +1 more source

[Alcoholic hepatitis].

Arquivos de gastroenterologia, 1983
openaire   +3 more sources

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

Addiction, EarlyView.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez, Abraham Bailén Torregrosa, Francisco Navarrete, Auxiliadora Aracil‐Fernández, Gabriel Rubio, Jorge Manzanares   +5 more
wiley   +1 more source

The association of methadone use with physical function and frailty among persons who inject drugs

Addiction, EarlyView.
Abstract Background and Aims Persons who inject drugs (PWID) experience a high burden of early‐onset frailty, primarily due to multifactorial causes such as infections (human immunodeficiency virus [HIV], hepatitis C virus [HCV]), substance use, and polypharmacy.
Grace L. Kulik, Hsing‐Yu Hsu, Jacqueline Rudolph, Yutong Jiang, Kristine M. Erlandson, Damani A. Piggott, Shruti Mehta, Jeremy D. Walston, Gregory Kirk, Todd T. Brown, Jing Sun   +10 more
wiley   +1 more source

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Biliary Glutathione as a Potential Marker for Viability Assessment of Cholangiocytes During Normothermic Machine Perfusion of Livers

Artificial Organs, EarlyView.
This study identifies biliary glutathione concentration during normothermic machine perfusion as a potential biomarker for biliary viability. Increasing GSH levels correlate with fewer biliary complications post‐transplant, supporting its role in assessing graft quality and improving decision‐making in liver transplantation.
Christina Bogensperger, Hannah Esser, Florian Ponholzer, Benno Cardini, Julia Hofmann, Franka Messner, Rupert Oberhuber, Thomas Resch, Dietmar Öfner, Stefan Schneeberger, Annemarie Weissenbacher   +10 more
wiley   +1 more source