Results 231 to 240 of about 75,203 (286)
Hepatology Research, EarlyView.Zinc deficiency is frequently seen in patients with chronic liver disease and is linked to poor appetite and nutritional status. We found that switching to zinc histidine hydrate increased zinc levels within a short period and was associated with improved appetite.
Yoshihito Uchida +9 more
wiley +1 more source
Hepatology Research, EarlyView.Patients with hepatocellular carcinoma (HCC) as well as chronic kidney disease (CKD) are high‐risk individuals, making it challenging to accurately predict their survival. We found that the PALBI grade model when combined with other patient's clinical and tumor‐related factors, forms a new and highly accurate prediction tool to estimate their ...
Jihye Lim +2 more
wiley +1 more source
Hepatology Research, EarlyView.Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura +26 more
wiley +1 more source
A Novel Diagnostic Approach for Hepatocellular Carcinoma Using Glycosylated Ferritin
Hepatology Research, EarlyView.The percentage of glycosylated ferritin relative to total ferritin (%GF) is a novel biomarker for hepatocellular carcinoma (HCC), showing diagnostic performance comparable to that of AFP and DCP. We developed the GFAD index by integrating age, sex, %GF, AFP, and DCP, achieving improved diagnostic accuracy with high sensitivity and specificity. ABSTRACT
Akiyo Ishiguro +11 more
wiley +1 more source
Hepatology Research, EarlyView.ABSTRACT Aim Steatotic liver disease (SLD) encompasses a heterogeneous spectrum with varying risks of hepatocellular carcinoma (HCC). Limited sample sizes limit the development of predictive models, particularly for rare outcomes. This study evaluated whether generative artificial intelligence (AI)‐based synthetic data augmentation can enhance HCC risk
Masaya Sato +12 more
wiley +1 more source
Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis
Hepatology Research, EarlyView.ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose +9 more
wiley +1 more source
Hepatology Research, EarlyView.Among patients with CP‐A HCC initially within the Japan criteria, some lose oncological eligibility for LT before hepatic decompensation. Further studies are needed to identify baseline factors associated with poor outcomes and to evaluate their relevance to future LT candidacy.
Akihiro Seki +16 more
wiley +1 more source
Systemic Treatment and Outcome in Erythrodermic Psoriasis: A Retrospective Multicenter Study
International Journal of Dermatology, EarlyView.This multicentre real‐world study illustrates the heterogeneity of systemic treatment approaches in erythrodermic psoriasis (EP) in Bavaria, Germany. Adverse events were more frequently observed with conventional therapies, whereas biologic therapies showed favorable outcomes.
Julian Kögel +15 more
wiley +1 more source
Iron Overload: Pathophysiology, Diagnosis and Monitoring
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil +3 more
wiley +1 more source