Results 21 to 30 of about 113,555 (294)

Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation [PDF]

, 2015
BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis in chronic liver disease; however, it is invasive, with the potential for serious complications.
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core   +2 more sources

Fungi–Bacteria Correlation in Alcoholic Hepatitis Patients

Toxins, 2021
Alcohol-related liver disease is one of the most prevalent types of chronic liver diseases globally. Alcohol-related liver disease begins with fatty liver, which further develops into hepatic inflammation, hepatocyte injury, and progresses to fibrosis ...
Bei Gao, Xinlian Zhang, Bernd Schnabl
doaj   +1 more source

Influence of doxorubicin on the extracellular matrix of the liver of rats under conditions of chronic alcoholic hepatitis

Regulatory Mechanisms in Biosystems, 2023
The liver has a high regenerative potential that is dependent on many factors, in particular adenosine monophosphate kinase signaling, however, long-term alteration, such as daily alcohol consumption, turns regeneration into a chronic disease such as ...
A. О. Mykytenko, O. Y. Akimov, G. A. Yeroshenko, K. N. Neporada   +3 more
doaj   +1 more source

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog [PDF]

, 2009
Alcohol synergistically enhances the progression of liver disease and the risk for liver cancer caused by hepatitis C virus (HCV). However, the molecular mechanism of this synergy remains unclear.
Asahina, Kinji, Deshaies, Raymond, Duan, Lewei, Dynnyk, Alla, Govindarajan, Sugantha, Lai, Michael M.-C., Liu, Helene Minyi, Machida, Keigo, Miyake, Kensuke, Mkrtchyan, Hasmik, Ou, Jing-hsiung James, Ray, Ratna, Seki, Ekihiro, Tsukamoto, Hidekazu   +13 more
core   +2 more sources

Hepatitis C virus related cirrhosis decreased as indication to liver transplantation since the introduction of direct-acting antivirals: A single-center study [PDF]

, 2018
AIM: To evaluate waiting list (WL) registration and liver transplantation (LT) rates in patients with hepatitis C virus (HCV)-related cirrhosis since the introduction of direct-acting antivirals (DAAs).
Angeli, Paolo, Burra, Patrizia, Cillo, Umberto, Ferrarese, Alberto, Gambato, Martina, Germani, Giacomo, Russo, Francesco Paolo, Senzolo, Marco, Shalaby, Sarah, Zanetto, Alberto, Zanus, Giacomo   +10 more
core   +1 more source

Treatment of Decompensated Alcoholic Liver Disease

International Journal of Hepatology, 2011
Alcoholic liver disease (ALD) is a spectrum ranging from simple hepatic steatosis to alcoholic hepatitis and cirrhosis. Patients with severe alcoholic hepatitis can have clinical presentation almost similar to those with decompensated cirrhosis.
John Menachery, Ajay Duseja
doaj   +1 more source

Leukemoid reaction in a patient with severe alcoholic hepatitis: A case report and review of literature

Medical Journal of Dr. D.Y. Patil University, 2016
Alcoholic hepatitis is a clinicopathologic syndrome that results from active alcohol consumption in a patient with or without underlying alcoholic liver disease.
Puneet Chabbra, Nikhil Gupta, Sarthak Malik, Paritosh Garg   +3 more
doaj   +1 more source

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Nature Communications, 2021
Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines ...
Mengfei Liu, Sheng Cao, Li He, Jinhang Gao, Juan P. Arab, Huarui Cui, Weixia Xuan, Yandong Gao, Tejasav S. Sehrawat, Feda H. Hamdan, Meritxell Ventura-Cots, Josepmaria Argemi, William C. K. Pomerantz, Steven A. Johnsen, Jeong-Heon Lee, Fei Gao, Tamas Ordog, Philippe Mathurin, Alexander Revzin, Ramon Bataller, Huihuang Yan, Vijay H. Shah   +21 more
doaj   +1 more source

Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]

, 2005
Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Derakhshan, M.H., Estakhri, A., Malekzadeh, R., Mohamadnejad, M., Mohammadkani, A., Montazeri, F., Montazeri, G., Nouri, N., Samiee, S., Zamani, F.   +9 more
core   +4 more sources

Sex difference in the interaction of alcohol intake, hepatitis B virus, and hepatitis C virus on the risk of cirrhosis [PDF]

, 2017
Background The joint effect of the interaction of alcohol intake, hepatitis B virus (HBV) and hepatitis C virus (HCV) on the risk of cirrhosis is still unexplored because a large sample size is required for this investigation.
Almasio, Piero Luigi, Andriulli, Angelo, Colloredo, Guido, Furlan, Caterina, Gaeta, Giovanni Battista, Morisco, Filomena, Pirisi, Mario, Rosina, Floriano, Sagnelli, Caterina, Sagnelli, Evangelista, Smedile, Antonina, Stroffolini, Tommaso   +11 more
core   +8 more sources