Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog [PDF]
, 2009 Alcohol synergistically enhances the progression of liver disease and the risk for liver cancer caused by hepatitis C virus (HCV). However, the molecular mechanism of this synergy remains unclear.
Asahina, Kinji +13 more
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New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance. [PDF]
, 2018 Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. HCC initiates as a consequence of chronic liver damage and inflammation caused by hepatitis B and C virus infections, excessive alcohol consumption, or non ...
Karin, Michael
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Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]
, 2005 Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Derakhshan, M.H. +9 more
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Pentoxifylline for alcoholic hepatitis [PDF]
Cochrane Database of Systematic Reviews, 2009 Alcoholic hepatitis is a life-threatening disease, with an average mortality of approximately 40%. There is no widely accepted, effective treatment for alcoholic hepatitis. Pentoxifylline is used to treat alcoholic hepatitis, but there has been no systematic review to assess its effects.To assess the benefits and harms of pentoxifylline in alcoholic ...
Whitfield, Kate +3 more
openaire +3 more sources
Treatment of Decompensated Alcoholic Liver Disease
International Journal of Hepatology, 2011 Alcoholic liver disease (ALD) is a spectrum ranging from simple hepatic steatosis to alcoholic hepatitis and cirrhosis. Patients with severe alcoholic hepatitis can have clinical presentation almost similar to those with decompensated cirrhosis.
John Menachery, Ajay Duseja
doaj +1 more source
Medical Journal of Dr. D.Y. Patil University, 2016 Alcoholic hepatitis is a clinicopathologic syndrome that results from active alcohol consumption in a patient with or without underlying alcoholic liver disease.
Puneet Chabbra +3 more
doaj +1 more source
Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
Nature Communications, 2021 Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines ...
Mengfei Liu +21 more
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Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]
, 2017 Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth +6 more
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Differences between Infected and Noninfected Patients with Acute Alcoholic Hepatitis
Canadian Journal of Infectious Diseases, 1992 The medical records of 97 patients with alcoholic hepatitis, including 20 with coexisting bacterial infections and 77 with no evidence of bacterial infection, were reviewed to determine whether commonly employed tests would be useful in distinguishing ...
GY Minuk, A Cohen, V Thompson
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Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
, 2014 Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
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