Results 41 to 50 of about 49,835 (356)

Can brewer-sponsored ‘drink responsibly’ warning message be effective without alcohol policies in Nigeria? [PDF]

, 2014
Alcohol availability, use and misuse and their related problems are rising in many parts of the African continent and this has been attributed to many factors such as non-existent or ineffective regulatory measures.
Anderson P., De Bruijn A., Dimah A., Dowling N., Dumbili E.W., Emeka W. Dumbili, Farrell T., Fenaughty A.M., Fisher H.R., Ibanga A., Isichei H., Jernigan D.H., Laughery K.R., Obot I.S., Obot I.S., Umoh O.O., World Health Organization   +16 more
core   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

State of endogenous intoxication and immune-inflammatory response in patients with alcoholic liver cirrhosis associated with non-alcoholic fatty liver disease

Gastroenterologìa, 2019
Background. The purpose was to evaluate the state of endogenous intoxication and immune-inflammatory response in patients with alcoholic liver cirrhosis (ALC) associated with non-alcoholic fatty liver disease (NAFLD), depending on the stage of ...
N.R. Matkovska, N.H. Virstiuk, U.V. Balan   +2 more
doaj   +1 more source

MetalCenter‐Dependent Selectivity Divergence in MN4 Single‐Atom Catalysts for Aerobic HMF Oxidation

Advanced Science, EarlyView.
Two single‐atom catalysts with M‐N4 configurations (FeN4 and CoN4) were developed for selective HMF oxidation. FeN4 achieves 93.9% selectivity toward FFCA via superoxide anions (O2•−), while CoN4 preferentially produces FDCA through hydroxyl radicals (•OH). DFT calculations reveal that distinct adsorption energies and charge redistribution at the metal
Haoyu Wang, Zhilong Ye, Weihao Wang, Zhi Hu, Qing Tian, Jie Gao, Lianbing Zhang   +6 more
wiley   +1 more source

Increase in Serum MMP-9 and TIMP-1 Concentrations during Alcohol Intoxication in Adolescents—A Preliminary Study

Biomolecules, 2022
Background: Alcohol consumption by adolescents is responsible for a number of adverse health and social outcomes. Despite the well-established effect of alcohol use on the development of alcoholic liver disease, the relationship between the pattern of ...
Katarzyna Zdanowicz, Monika Kowalczuk-Kryston, Witold Olanski, Irena Werpachowska, Wlodzimierz Mielech, Dariusz Marek Lebensztejn   +5 more
doaj   +1 more source

Drug addiction as a physical disease:The role of physical dependence and other chronic drug-induced neurophysiological changes in compulsive drug self-administration [PDF]

, 1998
Physical-dependence-based theories of addiction regard compulsive drug taking as the behavioral manifestation of a desperate need to relieve aversive autonomic withdrawal symptoms.
Lyvers, Michael
core   +1 more source

Orthogonal Design of Competing Deprotonation Process in Cation‐Mediated Ni(OH)2 for Achieving Industrial Level Biomass Electrooxidation

Advanced Science, EarlyView.
A Cu‐mediated Ni(OH)2 catalyst with orthogonal activity by precise valence engineering simultaneously accelerates rate‐determining aldehyde C─H activation in HMF oxidation and impedes O─H deprotonation in competing OER. This multi‐functional synergistic catalysis enables FDCA production at industrial‐level current densities without sacrificing FEFDCA ...
Junge Yang, Zhengjie Chen, Lili Zhang, Tao Zhang, Shida Bao, Jing Peng, Hui Pan, Hui‐Ming Cheng   +7 more
wiley   +1 more source

Predictors of Mortality in Methanol Poisoning: A Systematic Review and Meta-analysis

International Journal of Medical Toxicology and Forensic Medicine
Background: Today, methanol intoxication is increasing. Identifying mortality predictors has a significant correlation with poisoning progress. This meta-analysis study aimed to identify and evaluate mortality predictors for methanol poisoning.
Farzad Gheshlaghi, Mohammad Reza Rezaei, Nastaran Eizadi-Mood, Farinaz Fattahi, Mohammad Nazarianpirdosti, Aisan Ghasemi Oskui   +5 more
doaj   +1 more source

The abuse ofalcohol by children and young people in Poland and in the world 1

Pediatria i Medycyna Rodzinna, 2015
Alcohol is an indispensable element of contemporary culture, which emphasises the role it plays in interpersonal contacts. These days it appears at most social and business meetings. It is one of the most commonly used psychoactive substances.
Katarzyna Resler, Dorota Cichosz
doaj   +1 more source

Tendencias en el consumo de alcohol en adolescentes escolarizados en España (2010-2018)

Gaceta Sanitaria, 2021
Resumen: Objetivo: Analizar las tendencias en el consumo de cerveza, vino y licores destilados, así como de los episodios de embriaguez de los chicos y chicas adolescentes en España, en 2010, 2014 y 2018, por sexo y edad.Método: La muestra está formada ...
Eva Leal-López, Inmaculada Sánchez-Queija, Francisco Rivera, Carmen Moreno   +3 more
doaj   +1 more source