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Liver Transplantation for Alcoholic Liver Disease
Transplantation, 2016Alcohol-related liver disease is the second most frequent indication for liver transplantation (LT), yet as many as 90% to 95% of patients with alcohol-related end-stage liver disease are never formally evaluated for LT. Furthermore, despite its significance as a cause of chronic liver disease and indication for LT, it has received little attention in ...
Addolorato, Giovanni +9 more
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Liver transplantation for alcoholic liver disease
Addiction Biology, 2001AbstractAlthough increasing numbers of alcoholic patients are being referred to liver transplant centres, liver transplantation for alcoholic liver disease still remains controversial, essentially because we are in an era of organ shortage. In fact, the main issue is the likelihood of relapse and its influence on outcome, because it is the possibility ...
Georges-Philippe, Pageaux +2 more
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Liver transplantation for alcoholic liver disease
Nature Reviews Gastroenterology & Hepatology, 1993Alcoholism is a disease of remission and relapse. A lapse in abstinence tends to be viewed as a failure to commit to abstinence, and an acknowledged relapse may lead to the patient's removal from the liver transplant list; however, such a relapse may actually offer insight into alcoholism.
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Liver transplantation for alcoholic liver disease
Clinical Transplantation, 1996AbstractOrthotopic liver transplantation (OLT) for individuals with alcoholic liver disease (ALD) remains controversial. This review was designed to evaluate the survival, recidivism, and rehabilitation of the alcoholic liver transplant recipient in a single transplant center. Methods: Between 10/86 and 11/92 203 liver transplants were performed in 179
G B, Zibari +6 more
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Alcoholic Liver Disease and Liver Transplantation
Clinics in Liver Disease, 2016Excessive alcohol use is a common health care problem worldwide and is associated with significant morbidity and mortality. Alcoholic liver disease represents the second most frequent indication for liver transplantation in North America and Europe. The pretransplant evaluation of patients with alcoholic liver disease should aim at identifying those at
Juan F, Gallegos-Orozco +1 more
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Liver Fibrosis in Alcoholic Liver Disease
Seminars in Liver Disease, 2015Excessive alcohol consumption causes a wide spectrum of liver disease, ranging from simple steatosis to severe forms of liver injury such as steatohepatitis, liver fibrosis, cirrhosis, and liver cancer. Moreover, alcohol consumption also accelerates liver fibrosis in patients with other types of liver diseases such as viral hepatitis and nonalcoholic ...
Ramon, Bataller, Bin, Gao
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Oxysterols and Alcoholic Liver Disease
Alcoholism: Clinical and Experimental Research, 1990A new theory is presented implicating oxidative cholesterol metabolism and oxysterols as possible factors in the development of alcoholic liver disease. Our present studies have revealed the accumulation of cholesta‐3,5‐dien‐7‐one, 13.05 ± 2.75 μg/g (n = 8), and cholesta‐4,6‐dien‐3‐one, 2.26 ± 0.88 μg/g (n = 8) in fatty alcoholic liver, as compared ...
M T, Ryzlak +3 more
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Spectrum of Alcoholic Liver Disease
Clinics in Liver Disease, 2016Liver disease from excessive alcohol consumption is an important cause of morbidity and mortality worldwide. There is a clear relationship between alcohol and a variety of health and socioeconomic problems. According to the World Health Organization, 3.3 million people die of alcohol-related causes annually.
Kristina Rachel, Chacko, John, Reinus
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Cytokines in Alcoholic Liver Disease
Seminars in Liver Disease, 1999Cytokines are low-molecular-weight mediators of cellular communication produced by multiple cell types in the liver, with the Kupffer cell critically important. Inflammatory cytokines such as tumor necrosis factor, interleukin-1, and interleukin-8, and hepatic acute-phase cytokines such as interleukin-6 play a role in modulating certain metabolic ...
C J, McClain +4 more
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The Spectrum of Liver Disease in Alcoholism
Australian and New Zealand Journal of Medicine, 1975Summary: Liver biopsies obtained from 100 alcoholic patients attending a clinic primarily for the management of their alcoholism, have been reviewed. The morphological appearances have been correlated with histories of alcohol consumption and with clinical and biochemical findings.There were 77 men and 23 women.
P S, Bhathal +4 more
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