Results 51 to 60 of about 128,863 (140)

Diabetic Polyneuropathy Patients Exhibit an Altered Skeletal Muscle Proteome Phenotype

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Purpose Diabetic polyneuropathy (DPN) is a debilitating complication of diabetes that affects motor nerves and may impair skeletal muscle health. This study investigated skeletal muscle proteomic alterations associated with DPN compared with type 2 diabetes without DPN (T2D) and healthy controls (CON).
Frederik Forsberg Thybo, Karolina Snopek Khan, Jesper Emil Jakobsgaard, Henning Andersen, Kristian Vissing, Johan Palmfeldt   +5 more
wiley   +1 more source

Diabetic Peripheral Neuropathy With Low Appendicular Muscle Mass Is Associated With Osteoporosis, Falls, and Fractures

Journal of Diabetes, Volume 18, Issue 11, November 2026.
Diabetics have higher risks of osteoporosis, falls, and fractures; higher grip strength predicts lower risks. In both cross‐sectional and longitudinal data, diabetic patients with both peripheral neuropathy and low appendicular muscle mass have the highest risks of osteoporosis and falls.
Biao Zheng, Yongze Zhang, Dan Liang, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan   +6 more
wiley   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, Volume 100, Issue 4, Page 781-787, October 2026.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Glass shape influences consumption rate for alcoholic beverages [PDF]

, 2012
Background: High levels of alcohol consumption and increases in heavy episodic drinking (binge drinking) are a growing public concern, due to their association with increased risk of personal and societal harm.
George Stothart, Marcus R. Munafò, Munafò Marcus R., Stothart, George, Marcus R Munafò, Nicholas E. Scott-samuel, Nicholas E Scott-Samuel, Attwood, Angela S., Munafo, Marcus R., Angela S. Attwood, Scott-Samuel Nicholas E., Scott-Samuel, Nicholas E., Angela S Attwood, Stothart George, Attwood Angela S.   +14 more
core   +2 more sources

Protective Role of Folic Acid and Vitamin B12 Against Chronic Ivermectin‐Induced Reproductive Damage: Oxidative Stress, Immunohistochemical Changes (Caspase‐3, Bax, BCL2, and PCNA Expressions) and Mitochondrial 16S rRNA Analysis

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Twenty eight rats were divided into four groups (7 rats per group): Control group, Ivermectin group (IVM group), Ivermectin + Folic acid group (IVM + FA group), and Ivermectin + Vit.B12 group (IVM + Vit.B12 group). Blood and semen samples were collected to assess testosterone and semen parameters.
Yahia A. Amin, Asmaa M. Mosa, Rana A. Ali, Seham A. Mobarak, Zeinab A. Mar'ie   +4 more
wiley   +1 more source

Wernicke encephalopathy in non-alcoholic patients following gastrointestinal procedures: a systematic review

Frontiers in Surgery
BackgroundWernicke encephalopathy (WE) is a serious neurological disorder often linked to alcohol use but can also occur under non-alcoholic conditions, particularly following gastrointestinal (GI) procedures.
Hala Abu-Qasem, Husna Irfan Thalib, Zainab Shoeb Ghazi, Reem Tageldin, Yara Alras, Hanin Faisal, Laiba Khan, Abderrahman Ouban, Mounzer Yassin-Kassab   +8 more
doaj   +1 more source

The α2‐Subunit Preferring GABA Positive Allosteric Modulator, N‐Desmethyl‐Clobazam in Peripheral Neuropathic Pain Patients: Results of a Phase IIa Randomised Placebo‐Controlled Ascending Dose Study

European Journal of Pain, Volume 30, Issue 9, October 2026.
ABSTRACTBackgroundN‐desmethyl clobazam (NDMC), an α2‐preferring‐α1‐sparing‐GABAA modulator, was promising in preclinical models and Phase I studies, demonstrating antihyperalgesic properties without associated sedation. This Phase IIa trial aimed at exploring the effect of NDMC in peripheral neuropathic pain (NP) patients.MethodRandomised, ascending ...
M. Besson, A. Matthey, Y. Daali, A. Ramsahye, C. Samer, J. Desmeules, F. Curtin   +6 more
wiley   +1 more source

Diagnostic performance of SD‐ΔRR during physical stressors for identifying diabetic sensorimotor polyneuropathy

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1770-1781, October 2026.
Study population, methodology and key findings of the study. ABSTRACT Aims This study aimed to evaluate the clinical efficacy of SD‐ΔRR as a novel methodology for short‐duration heart rate variability (HRV) assessment for the diagnosis of diabetic sensorimotor polyneuropathy (DSPN) in patients with diabetes.
Katsuyoshi Katayama, Haruhito A. Uchida, Toshihiko Nagao, Jun Eguchi, Kenji Tsuji, Yoshinori Matsumoto, Ichiro Nojima, Keiko Tanaka, Hidemi Takeuchi, Yasuhiro Onishi, Rika Takemoto, Satoshi Miyamoto, Kenichi Shikata, Jun Wada   +13 more
wiley   +1 more source

A Review of the Effects of Omega-3 and Omega-6 on Alcoholic and Non-Alcoholic Fatty Liver [PDF]

Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in the liver not caused by excessive alcohol consumption. In contrast, alcoholic liver disease (ALD) is directly caused by it.
Darvishi, Mohammad, Alaa Toama, Mariam, K. Hadrawi, Salema, Adeli, Omid-Ali, Majid Alsaraf, Khulood, F. Ramadan, Montather, Pirhadi, Mohadeseh   +6 more
core   +1 more source

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1643-1657, October 2026.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh, Abdulnabi T Alattar, Ahmed Abdul Karim Hassoun, Afaf Alshammary, Hussein Elbadawi, Khaled Aldossari, Noor Al Busaidi, Saud Alsifri, Talal Muzaffar, Wiam I. Hussein, Christine Talaat, Abanoub Effat, Marwa Elsaghier, Rayaz A Malik   +13 more
wiley   +1 more source