Results 111 to 120 of about 66,025 (242)

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

Glia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford, James W. M. Kang, OIivia I. Davanzo, Hyunsol Lim, Sabrina Salberg, Marissa Srgo, Crystal Li, Gaelle M. Emvalomenos, Bianca Jupp, Matthew Long, Wayne Noonan, Mohammad B. Haskali, Richelle Mychasiuk, Kevin A. Keay, Luke A. Henderson   +14 more
wiley   +1 more source

Aldehyde Dehydrogenase-2 Alleviates Septic Myocardial Injury by Inhibiting Caspase-11-Mediated Noncanonical Pyroptosis. [PDF]

Cardiovasc Ther
Liang H, He Y, Wang Y, Zhang R, Yu M, Ye H, Wang J, Gao Q.   +7 more
europepmc   +1 more source

Myocardial Lipid Metabolism Imbalance: The Pathological Core and Novel Diagnostic‐Therapeutic Directions of Cardiovascular Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie, Qun Zeng, Hongrui Wang, Meihua She   +3 more
wiley   +1 more source

Aldehyde Dehydrogenase 2 Gene Polymorphism and Alcohol Consumption Are Associated With Nephrolithiasis in a Chinese Population. [PDF]

Mol Genet Genomic Med
Liu T, Lv YQ, Huang XL, Xie YL, Ye Y, Chen Y, Feng C, Wang QY, Mo ZN, Liao M, Li TY, Liao J.   +11 more
europepmc   +1 more source

Atorvastatin Reduces Alcohol‐Related Cardiac and Liver Tissue Damage, Oxidative Stress, Inflammation, Apoptosis, and Thiol‐Disulfide Imbalance in Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Atorvastatin (40 mg/kg) inhibited fibrosis, hypertrophy, apoptosis, inflammation, and oxidative stress caused by alcohol consumption. It may contribute to the regulation of mitochondrial function and thiol/disulfide balance by limiting alcohol‐related heart and liver damage.
Cumaali Demirtas, Şahhan Kılıç, Mert Babaoğlu, Süha Asal, Elif Gökçe Tenekeci, Hakan Beyaztaş, Eray Metin Guler, Salime Pelin Erguven, Kubra Sevgin   +8 more
wiley   +1 more source

The Activation of Aldehyde Dehydrogenase 2 (ALDH2) by Alda-1 and Flurbiprofen as a Common Mechanism to Reduce Alcohol Intake in Rats. [PDF]

Int J Mol Sci
Torres JM, Ponce C, Pérez V, Gutiérrez-Vega I, Quintanilla ME, Vásquez D, Rivera-Meza M.   +6 more
europepmc   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

A Novel Blend of Dietary Ingredients Mitigates Blood and Breath Ethanol Levels After Acute Alcohol Intake

Nutrition and Dietary Supplements
Michael B La Monica, Betsy Raub, Shelley Hartshorn, Ashley Gustat, Jodi Grdic, Jennifer Sandrock The Center for Applied Health Sciences, Canfield, OH, USACorrespondence: Michael B La Monica, The Center for Applied Health Sciences, 6570 Seville Dr ...
La Monica MB, Raub B, Hartshorn S, Gustat A, Grdic J, Sandrock J   +5 more
doaj  

Effect of genetic polymorphisms of aldehyde dehydrogenase 2 on the efficacy of intermittent parathyroid hormone treatment and bone mineral density: A retrospective multicenter study. [PDF]

Osteoporos Sarcopenia
Obara H, Tajima T, Tsukamoto M, Yamanaka Y, Suzuki H, Nagashima M, Nishida S, Ikeda S, Maekawa K, Sakai A.   +9 more
europepmc   +1 more source

Aldehyde Dehydrogenase [PDF]

, 2020
openaire   +1 more source