Results 131 to 140 of about 41,156 (268)

Aldolases of the DhnA family: a possible solution to the problem of pentose and hexose biosynthesis in archaea [PDF]

, 2000
Michael Y. Galperin
openalex   +1 more source

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

In Vivo Functional Characterization of the Aldolase B Gene Enhancer [PDF]

, 2002
Claudine Grégori, Arlette Porteu, Claudia Mitchell, Axel Kahn, Anne-Lise Pichard   +4 more
openalex   +1 more source

Cell‐Type‐Dependent Metabolic Compensation Preserves Photoreceptor Survival Through Pyruvate Kinase Isoform Balance

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
We investigated the roles of PKM2, PKM1, and LDHA in retinal metabolism and structural integrity. In the normal retina, these enzymes are maintained at defined levels that support photoreceptor function. Rod‐specific deletion of LDHA, alone or with PKM2, caused age‐dependent degeneration, as PKM1 induction did not reach levels comparable to PKM2.
Ammaji Rajala, Larissa J. Trevino, Tyler M. Black, Raju V. S. Rajala   +3 more
wiley   +1 more source

Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion. [PDF]

Nat Cell Biol
Hoffmann L, Duchmann M, Lazarow K, Huang YH, Lukas F, Lo WT, Feil R, Schmied C, Lehmann M, Lunn JE, Piazza I, von Kries JP, Haucke V, Maritzen T.   +13 more
europepmc   +1 more source

Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species

Allergy, Volume 81, Issue 5, Page 1846-1850, May 2026.
Kelvin Fu‐Kiu Ao, Judy Kin Wing Ng, Cherie Tsz‐Yiu Law, Weixue Mu, Shanshan Li, Christine Yee Yan Wai, Man Fung Tang, Shannon Wing Ngor Au, Xiaoyu Liu, Ting Fan Leung, Qing Xiong, Stephen Kwok‐Wing Tsui   +11 more
wiley   +1 more source

Natural and Synthetic Metabolic Architectures

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Metabolism yields function through architecture, not through isolated parts. This Perspective article discusses how design can move from components to connectivity and then to architectural regimes that account for space, time, and routing. The framework links understanding to engineering and helps explain why microbial engineering meets challenges ...
Pablo I. Nikel
wiley   +1 more source

Generation and Characterization of a Genetically Modified <i>Zea mays</i> Line with a Knockdown of Hypoxia-Dependent microRNA775A. [PDF]

Int J Mol Sci
Fedorin DN, Khomutova AE, Eprintsev AT, Igamberdiev AU.   +3 more
europepmc   +1 more source

Modulation of glutamate metabolism in Niemann-pick disease type C1 mice. [PDF]

Mol Genet Metab Rep
Cougnoux A, Alvarez CS, Maria AG, Hernandez E, Cawley NX, Davidson CD, Porter FD.   +6 more
europepmc   +1 more source

Characterization of Chloroplastic Fructose 1,6-Bisphosphate Aldolases as Lysine-methylated Proteins in Plants [PDF]

, 2012
Morgane Mininno, Sabine Brugière, Virginie Pautre, Annabelle Gilgen, Sheng Ma, Myriam Ferro, Marianne Tardif, Claude Alban, Stéphane Ravanel   +8 more
openalex   +1 more source