Results 231 to 240 of about 793,397 (347)

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Cutaneous Vulvar Tuberculosis Over an Episiotomy Scar in an Immunocompetent Patient. [PDF]

Cureus
Suárez Garcia ME, Mendez S, Romero Ríos CK, Aragón Conrado LE, Robleto FJ, Moreno Cabrera CS.   +5 more
europepmc   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh, Zahra Haghighijoo, Akanksha Gurtu, Nolan M. Dvorak, Timothy J. Baumgartner, Nana A. Goode, Jully Singh, Matteo Bernabucci, Adam T. Szafran, Michael J. Bolt, Michael A. Mancini, Natalie M. Dvorak, Marijn Lijffijt, Zhiqing Liu, Yu Xue, Alyssa K. Thomas, Alejandro Villasante‐Tezanos, Balaji Krishnan, Jia Zhou, Fernanda Laezza   +19 more
wiley   +1 more source

Preoperative Motor and Sensory Dysfunction as Predictors of Permanent Neurological Deficit in Spinal Tuberculosis: A Retrospective Cohort Study. [PDF]

Cureus
Wangapakul T, Becerril-Mejía A, Riley Moguel AE, Nuñez-Lupaca JN, Flores Palacios RJ, Díaz Lagunas JO, Wong Achi X.   +6 more
europepmc   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Hypernatremia-Hypodipsia

Revista de Nefrología, Diálisis y Trasplante, 2014
Carolina Mroue, Jorge Cestari, Guillermo Alemano Guillermo Alemano   +2 more
doaj  

Use of Radiotherapy in the Treatment of Non-melanoma Skin Cancer: Experience From a Regional Referral Center. [PDF]

Cureus
Colis Arenas OA, Navarro Montellano KC, Valdivia Esquivel CA.   +2 more
europepmc   +1 more source

NAADF: Globally Illuminated Voxel Worlds Accelerated with Nested Axis‐Aligned Distance Fields

Computer Graphics Forum, EarlyView.
Abstract Achieving realistic rendering of 3D scenes in real time using path tracing is challenging due to the high sample count required, with ray tracing as the bottleneck. Focusing on voxels as a geometry representation offers significant opportunities for optimizations, especially for tracing the rays, but also for computing the samples.
A. Ulschmid, M. Ott, J. Macho, M. Wimmer, S. Ohrhallinger   +4 more
wiley   +1 more source

Step-by-Step Clipping of Clustered Ipsilateral Anterior Circulation Aneurysms via an Extended Minipterional Approach. [PDF]

Cureus
Serrano-Rubio A, Wong-Achi X, Riley-Moguel AE, Flores-Vázquez JG, Nathal E.   +4 more
europepmc   +1 more source

Spiders in the mosaic: How habitat heterogeneity and structure drive local spider diversity in a Mediterranean forest

Ecological Entomology, EarlyView.
We assessed alpha‐ and beta‐diversity patterns of spiders across different forests and across vegetation layers (ground, shrub, low canopy) at local spatial scales across various Mediterranean forest types. Across forests, alpha‐diversity increased with habitat heterogeneity, which also drove beta‐diversity patterns across plots .
Manuel Marquerie‐Córdoba, Cesc Múrria, Cristina Ramos, Alejandro Sánchez, Albert Sevil, Alba Enguídanos García, Roger Puig‐Gironès, Joan Real, Miquel A. Arnedo   +8 more
wiley   +1 more source