Results 31 to 40 of about 793,397 (347)
Orchestrating high-throughput genomic analysis with Bioconductor
Nature Methods, 2015 Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology.W. Huber, V. Carey, R. Gentleman, S. Anders, Marc Carlson, B. Carvalho, H. C. Bravo, Sean R. Davis, L. Gatto, T. Girke, R. Gottardo, F. Hahne, Kasper D. Hansen, R. Irizarry, Michael Lawrence, M. Love, James MacDonald, Valerie Obenchain, Andrzej K. Oles, Hervé Pagès, Alejandro Reyes, P. Shannon, G. Smyth, Dan Tenenbaum, L. Waldron, Martin T. Morgan +25 moresemanticscholar +1 more sourceRevisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde +5 morewiley +1 more sourcePlasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
Advanced Materials, EarlyView.This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks +16 morewiley +1 more sourceCOVID-19 associated pulmonary aspergillosis in ICU patients: Report of five cases from Argentina
Medical Mycology Case Reports, 2021 Invasive pulmonary aspergillosis is a complication in critically ill patients with acute respiratory distress syndrome, especially those with severe coronavirus disease-associated pneumonia.María Fernanda Benedetti, Katherine Hermida Alava, Judith Sagardia, Roberto Corella Cadena, Diego Laplume, Paula Capece, Gladys Posse, Alejandro David Nusblat, María Luján Cuestas +8 moredoaj +1 more sourceA New Equation to Estimate Glomerular Filtration Rate
Annals of Internal Medicine, 2009 Background Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher levels. Objective To develop a new estimating A. Levey, L. Stevens, C. Schmid, Y. Zhang, Alejandro F Castro, H. Feldman, J. Kusek, P. Eggers, F. van Lente, T. Greene, J. Coresh +10 moresemanticscholar +1 more sourceSolvent‐Free Thermal Defect Engineering in Molecular Frameworks With Volatile Linkers
Advanced Materials, EarlyView.Thermal removal of neutral volatile linkers enables precise and solvent‐free generation of metal vacancies in MOFs. This strategy affords redox‐stable, coordinatively unsaturated FeII sites with tunable spin, ligand coordination, and catalytic behavior. The approach offers a general route to design defect‐functional materials through local coordination Sonia Martínez‐Giménez, Alejandro Orellana‐Silla, Marta Galbiati, Efrén Navarro‐Moratalla, Luca Braglia, Sara Stolfi, José Antonio Real, Víctor Rubio‐Giménez, Sergio Tatay, Carlos Martí‐Gastaldo +9 morewiley +1 more sourceLight and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems
Angewandte Chemie, EarlyView.Here, we report a photoswitchable synthetic peptide that, under light energy cycles, exhibits supramolecular polymorphism coupled to darkness‐driven structural self‐selection. We demonstrate that light sustains a transient assembled state in the form of helical nanoribbons, hindering the system from undergoing a transition to the disassembled state ...Alejandro Méndez‐Ardoy, Nicolas Cissé, Adrian Sanchez‐Fernandez, Patricia Fulias‐Guzmán, Marc C. A. Stuart, Tibor Kudernac, Javier Montenegro +6 morewiley +2 more sourcesPrevalence and architecture of de novo mutations in developmental disorders
Nature, 2017 The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important genes.Jeremy F. Stephen Tomas W. Joanna Elena Diana Alejandro S McRae Clayton Fitzgerald Kaplanis Prigmore Rajan S, J. McRae, Stephen Clayton, Tomas W. Fitzgerald, J. Kaplanis, E. Prigmore, D. Rajan, A. Sifrim, Stuart Aitken, N. Akawi, M. Alvi, K. Ambridge, Daniel M. Barrett, Tanya Bayzetinova, Philip Jones, W. Jones, D. King, N. Krishnappa, Laura E. Mason, T. Singh, A. Tivey, Munaza Ahmed, U. Anjum, H. Archer, R. Armstrong, J. Awada, M. Balasubramanian, S. Banka, D. Baralle, A. Barnicoat, Paul Batstone, D. Baty, C. Bennett, J. Berg, B. Bernhard, A. Bevan, M. Bitner-Glindzicz, Edward Blair, Moira Blyth, D. Bohanna, L. Bourdon, D. Bourn, L. Bradley, A. Brady, Simon Brent, C. Brewer, K. Brunstrom, D. Bunyan, J. Burn, N. Canham, B. Castle, K. Chandler, Elena Chatzimichali, D. Cilliers, Angus Clarke, S. Clasper, J. Clayton-Smith, V. Clowes, A. Coates, Trevor Cole, Irina Colgiu, Amanda Collins, M. Collinson, F. Connell, N. Cooper, H. Cox, L. Cresswell, G. Cross, Yanick J. Crow, Mariella D’Alessandro, T. Dabir, R. Davidson, Sally Davies, Dylan H. de Vries, J. Dean, C. Deshpande, G. Devlin, A. Dixit, A. Dobbie, A. Donaldson, D. Donnai, D. Donnelly, C. Donnelly, Angela Douglas, S. Douzgou, A. Duncan, J. Eason, S. Ellard, Ian Ellis, F. Elmslie, K. Evans, S. Everest, T. Fendick, R. Fisher, F. Flinter, N. Foulds, A. Fry, A. Fryer, C. Gardiner, L. Gaunt, N. Ghali, Richard J. Gibbons, H. Gill, J. Goodship, D. Goudie, Emma V. Gray, A. Green, Philip Greene, L. Greenhalgh, S. Gribble, R. Harrison, L. Harrison, V. Harrison, R. Hawkins, Liu He, Stephen W. Hellens, A. Henderson, S. Hewitt, Lucy Hildyard, E. Hobson, S. Holden, M. Holder, S. Holder, G. Hollingsworth, T. Homfray, M. Humphreys, J. Hurst, Ben Hutton, S. Ingram, M. Irving, L. Islam, Andrew Jackson, J. Jarvis, Lucy Jenkins, Diana S. Johnson, Elizabeth A. Jones, D. Josifova, S. Joss, B. Kaemba, S. Kazembe, Rosemary Kelsell, B. Kerr, Helen Kingston, U. Kini, E. Kinning, Gail A Kirby, C. Kirk, Emma C. Kivuva, A. Kraus, Dhavendra Kumar, V. K. A. Kumar, K. Lachlan, W. Lam, A. Lampe, C. Langman, M. Lees, D. Lim, C. Longman, G. Lowther, S. Lynch, A. Magee, E. Maher, Alison M. Male, S. Mansour, K. Marks, K. Martin, U. Maye, Emma McCann, V. Mcconnell, M. McEntagart, R. McGowan, Kirsten McKay, S. McKee, D. McMullan, S. McNerlan, C. Mcwilliam, S. Mehta, K. Metcalfe, A. Middleton, Z. Miedzybrodzka, E. Miles, S. Mohammed, T. Montgomery, D. Moore, S. Morgan, J. Morton, H. Mugalaasi, V. Murday, Helen R Murphy, S. Naik, Andrea H Németh, L. Nevitt, R. Newbury-Ecob, Andrew Norman, R. O’Shea, C. Ogilvie, K. Ong, Soo-Mi Park, M. Parker, Chirag Patel, J. Paterson, S. Payne, D. Perrett, Julie M. Phipps, D. Pilz, M. Pollard, C. Pottinger, Joanna Poulton, N. Pratt, K. Prescott, S. Price, A. Pridham, A. Procter, H. Purnell, O. Quarrell, N. Ragge, R. Rahbari, Joshua C Randall, J. Rankin, L. Raymond, D. Rice, L. Robert, E. Roberts, J. Roberts, P. Roberts, G. Roberts, A. Ross, E. Rosser, A. Saggar, Shalaka Samant, Julian Sampson, R. Sandford, A. Sarkar, Susann Schweiger, R. Scott, I. Scurr, A. Selby, A. Seller, C. Sequeira, N. Shannon, S. Sharif, C. Shaw-Smith, Emma Shearing, Debbie Shears, E. Sheridan, I. Simonic, R. Singzon, Zara Skitt, Audrey Smith, Kath Smith, S. Smithson, L. Sneddon, M. Splitt, M. Squires, Fiona J Stewart, Helen Stewart, V. Straub, M. Suri, V. Sutton, G. Swaminathan, E. Sweeney, K. Tatton-Brown, C. Taylor, R. Taylor, M. Tein, I. Temple, J. Thomson, M. Tischkowitz, S. Tomkins, A. Torokwa, B. Treacy, C. Turner, Peter Turnpenny, C. Tysoe, A. Vandersteen, V. Varghese, P. Vasudevan, Parthiban Vijayarangakannan, J. Vogt, E. Wakeling, Sarah Wallwark, J. Waters, A. Weber, D. Wellesley, M. Whiteford, S. Widaa, Sarah Wilcox, Emily Wilkinson, Denise K. Williams, N. Williams, L. Wilson, G. Woods, C. Wragg, Michael Wright, L. Yates, Michael Yau, C. Nellåker, M. Parker, H. Firth, C. Wright, D. FitzPatrick, J. Barrett, M. Hurles +302 moresemanticscholar +1 more sourcePOM‐Based Water Splitting Catalyst Under Acid Conditions Driven by Its Assembly on Carbon Nanotubes
Advanced Materials, EarlyView.A newly‐engineered POM‐based electrocatalyst incorporating non‐innocent counter cations exhibits fast kinetics for either the OER or HER under strongly acidic conditions (1 m H2SO4), depending on whether it is assembled on carbon nanotubes (1@CNT) or physically mixed with them (1/CNT). In water‐splitting tests using a two‐electrode setup, these systems Eugenia P. Quirós‐Díez, Melanie Guillén‐Soler, Carlos Herreros‐Lucas, Alejandro López‐Moreno, José Manuel Vila‐Fungueiriño, Antonio Luis Llamas‐Saiz, Karol Strutyński, Manuel Melle‐Franco, María del Carmen Giménez‐López +8 morewiley +1 more sourceπ‐Extended COUPY Fluorophores for Targeted Near‐Infrared Fluorescence and Lifetime Imaging in Live Cells
Angewandte Chemie, EarlyView.π‐Extended COUPY dyes, obtained by vinylogation of coumarin‐based COUPY scaffolds, shift absorption, and emission deep into the NIR region while preserving compactness and synthetic accessibility. These bright, photostable dyes enable live‐cell imaging, FLIM, and site‐specific peptide conjugation, offering a modular platform for targeted bioimaging and Diego Abad‐Montero, Manel Bosch, Rodrigo Garcés‐Castellanos, Michael Q. Schottenhamel, Sergio Pedraza‐Arevalo, Alejandro Ibáñez‐Costa, Justo P. Castaño, Tania García‐Becerra, Elena Rebollo, Marta E. Alberto, Antonio Francés‐Monerris, Vicente Marchán +11 morewiley +2 more sources