Results 261 to 270 of about 774,994 (289)

Commentary. The Diseases of Alexander the Great

Journal of the History of the Neurosciences, 2004
The accompanying articles that speculate that Alexander the Great had a traumatic carotid dissection or congenital cervical scoliosis demonstrate the difficulties in retrospective diagnosis as a historical enterprise. The extant primary sources were written centuries after Alexander's death and are ambiguous in their original languages, and even more ...
George K, York, David A, Steinberg
openaire   +2 more sources

Alexander's Disease

2014
Alexander's disease can occur at any age. Children typically present with delayed development, seizures, and macrocephaly, whereas older patients generally display bulbar symptoms. Myelin defects can be severe in younger patients, but subtle or absent in older patients.
openaire   +1 more source

Alexander disease: diagnosis with MR imaging.

AJNR. American journal of neuroradiology, 2001
To date, the demonstration of Rosenthal fibers on brain biopsy or autopsy specimens is considered a prerequisite for a definitive diagnosis of Alexander disease. We initiated a multiinstitutional survey of MR abnormalities in both presumed and confirmed cases of Alexander disease to assess the possibility of an MR-based diagnosis.MR imaging studies in ...
Van der Knaap, M. S., Naidu, S., Breiter, S. N., Blaser, S., Stroink, H., Springer, S., Begeer, J. C., Van Coster, R., Barth, P. G., Thomas, N. H., Valk, J., Powers, J. M.   +11 more
openaire   +3 more sources

Neuropsychological Functioning in Alexander Disease: A Case Series

Child Neurology Open, 2021
Alexandra C Kirsch, Deborah L Renaud, Michael J Zaccariello   +2 more
exaly  

Developmental Profiles in Children and Young Adults with Alexander Disease

Developmental Neurorehabilitation, 2023
Laura Zampini, Paola Zanchi
exaly  

GFAP variants leading to infantile Alexander disease: Phenotype and genotype analysis of 135 cases and report of a de novo variant

Clinical Neurology and Neurosurgery, 2021
Ali Reza Tavasoli, Mahmoud Reza Ashrafi, Nejat Mahdieh   +2 more
exaly  

GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease

Cell Stem Cell, 2018
E Tian, Xianwei Chen, Guihua Sun
exaly  

Alexander's Disease

Developmental Medicine & Child Neurology, 1993
openaire   +1 more source

Disorders of Astrocytes: Alexander Disease as a Model

Annual Review of Pathology: Mechanisms of Disease, 2017
James E Goldman
exaly  

Alexander's disease in infancy and childhood: a report of two cases

Acta Neuropathologica, 1992
J W Neal, G Cole, S J Wallace
exaly