Results 161 to 170 of about 56,565 (243)

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

Angewandte Chemie, EarlyView.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim, Sandra Liebscher, Rasmus Klintrot, Lorenzo Vallino, Marcelo Masman, Andreas H. Simon, Marianne Hahn, Sven Hennig, Saskia Neubacher, Frank Bordusa, Tom N. Grossmann   +10 more
wiley   +2 more sources

In Vivo Gastric Expression of FTO and MC4R in Sleeve Gastrectomy Patients: Diagnostic Utility Without Predictive Value for Weight Loss. [PDF]

Obes Surg
Hany M, ElDeeb MK, Elmongui E, Abouelnasr AA, El-Banna NA, Omer SM, Shaker SA, ElTahan RA.   +7 more
europepmc   +1 more source

Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics

Annals of Neurology, EarlyView.
Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino, Elena Sagues, Carlos Dier, Diego Ojeda, Samantha Saenz‐Hinojosa, Sebastian Sanchez, Ariel Vargas, Linder Wendt, Maria Belen Torres, Emily Garces, Alex Hanson, Navami Shenoy, Connor Aamot, Susan A. Walsh, Anil K. Chauhan, Gowri Anil‐Peethambar, Santiago Ortega‐Gutierrez, Jay Kinariwala, Mohamed Elshikh, Amir Shaban, Enrique C. Leira, Osorio Lopes Abath Neto, Malik Ghannam, Edgar A. Samaniego   +23 more
wiley   +1 more source

National Getis-Ord G_i*statistics datasets for select populations, 2019-2023 American community survey 5-year estimates. [PDF]

Data Brief
McGowan C, Alexandria SJ, Kershaw KN.
europepmc   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, EarlyView.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Effectiveness of an educational program on improving the knowledge and practice of environmental sustainability in dentistry among undergraduate students at Faculty of Dentistry in Egypt: an interventional study. [PDF]

BMC Med Educ
Bishr EM, Hussein MF, Ismail GA, Fetohy EM, El-Zoka AH.   +4 more
europepmc   +1 more source

The Effect of Silk on the Stabilization of Labile Enzyme Lipoxygenase

Advanced NanoBiomed Research, EarlyView.
Entrapping lipoxygenase within silk significantly extended its stability from under 24 h to 10 days. Variations in silk molecular weight and freeze‐drying conditions influenced silk properties and enzyme interactions. This stabilization is leveraged to develop a linoleic acid electrochemical biosensor, integrating lipoxygenase with horseradish ...
Jacopo Giaretta, Xinyu (Vivian) Xie, Sandra Spoa, Hien A. Tran, Syamak Farajikhah, Sepehr Talebian, Jelena Rnjak‐Kovacina, Fariba Dehghani   +7 more
wiley   +1 more source

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

Angewandte Chemie, EarlyView.
This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire, Wesley J. Olivier, Debabrata Maiti, Alex C. Bissember   +3 more
wiley   +2 more sources

Eco-enhanced silicone rubber composites reinforced with micro and nano iron slag and TiO₂ for thermal stability and radiation protection. [PDF]

Sci Rep
Khalil MM, Gouda MM, Moniem MSAE, Abbas MI, Abd-Elzaher M, Anas M, El-Khatib AM.   +6 more
europepmc   +1 more source