Results 31 to 40 of about 112,491 (292)

Etnicidad y emulación: estudio y desarrollo de la iconografía de la divinidad greco-egipcia Serapis = Ethnicity and Emulation: Study and Development of the Iconography of the greco-Egyptian Divinity Serapis

open access: yesEspacio, Tiempo y Forma. Serie II, Historia Antigua, 2020
El dios Serapis era una de las divinidades más importantes en la época de la conquista de Egipto por Alejandro Magno en 332 a.C. Este dios egipcio fue asociándose a distintos dioses griegos, helenizándose en un proceso de hibridación extendido a lo largo
Olga Termis Moreno
doaj   +1 more source

The Antioxidant defense Responses of Sea cucumber Holothuria polii Against Rickettsia-like organism (RLOs) Infection and Heavy Metal Pollution in Alexandria coast [PDF]

open access: yesJournal of Bioscience and Applied Research, 2017
Holothuria polii, the common black sea cucumber (Echinodermata, Holothuroidea), is abundant in the Mediterranean Sea along the Alexandria coast. This species was given great value commercially and for human consumption. The present study was objective to
Mohamed Elghazaly, Aml Ghoneim
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Alexandria Township Open Space Plan

open access: yes, 1992
The goal of the Alexandria Township Open Space Plan is to promote the preservation of land, vistas, and scenic roadways and ridge ways for the purpose of conservation, preservation, recreation, and the continuation of Alexandria's heritage.

core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Alexandria Township Open Space Plan

open access: yes, 1994
Alexandria's Open Space Plan was developed in 1992 by Robert Watrous and Lori Watrous-deVersterre, with assistance from other Alexandria Township Environmental Commission members and residents.

core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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