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Summarization: The Alfas porous stone (porolithos) excavated in Rethimnon, Crete, Greece, often features two material bands with similar mineralogical but different depositional characteristics and therefore different mechanical parameters.
Pavlos Nomikos +2 more
exaly +2 more sources
Summarization: This paper focuses on the experimental and numerical investigation of the size effect and the fracture process on the uniaxial compression strength (UCS) of the banded Alfas porous stone.
K Kaklis, Zach Agioutantis
exaly +2 more sources
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Drugs, 2008
Lutropin alfa is the first and only recombinant human form of luteinizing hormone (LH) developed for use in the stimulation of follicular development. Dose-finding studies revealed a significant dose-dependent increase in the rate of optimal follicular development among women with hypogonadotropic hypogonadism and profound LH deficiency (or=35 years ...
Sohita, Dhillon, Gillian M, Keating
openaire +2 more sources
Lutropin alfa is the first and only recombinant human form of luteinizing hormone (LH) developed for use in the stimulation of follicular development. Dose-finding studies revealed a significant dose-dependent increase in the rate of optimal follicular development among women with hypogonadotropic hypogonadism and profound LH deficiency (or=35 years ...
Sohita, Dhillon, Gillian M, Keating
openaire +2 more sources
Drugs, 2001
Darbepoetin alfa is a novel erythropoiesis-stimulating protein developed for the treatment of anaemia associated with chronic kidney disease. In single-dose studies in patients undergoing dialysis, the mean terminal half-life for intravenous darbepoetin alfa was approximately 3-fold longer than for intravenous recombinant human erythropoitin (r-HuEPO ...
T, Ibbotson, K L, Goa
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Darbepoetin alfa is a novel erythropoiesis-stimulating protein developed for the treatment of anaemia associated with chronic kidney disease. In single-dose studies in patients undergoing dialysis, the mean terminal half-life for intravenous darbepoetin alfa was approximately 3-fold longer than for intravenous recombinant human erythropoitin (r-HuEPO ...
T, Ibbotson, K L, Goa
openaire +2 more sources
Drugs of Today, 2004
Drotrecogin alfa (activated) is a human recombinant protein that is intravenously administered in a continuous, weight-based dose for patients with severe sepsis. In patients with severe sepsis, thrombin has been implicated in the interrelationship between the coagulation and inflammation pathways.
Michael J, Raggio, Peter E, Morris
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Drotrecogin alfa (activated) is a human recombinant protein that is intravenously administered in a continuous, weight-based dose for patients with severe sepsis. In patients with severe sepsis, thrombin has been implicated in the interrelationship between the coagulation and inflammation pathways.
Michael J, Raggio, Peter E, Morris
openaire +2 more sources
Drugs of Today, 2014
Mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome, is an inherited, lysosomal storage disorder caused by genetic mutations in N-acetylgalactosamine-6-sulfatase (GALNS) enzyme gene. GALNS is essential for breakdown of glycosaminoglycans.
openaire +2 more sources
Mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome, is an inherited, lysosomal storage disorder caused by genetic mutations in N-acetylgalactosamine-6-sulfatase (GALNS) enzyme gene. GALNS is essential for breakdown of glycosaminoglycans.
openaire +2 more sources
Clinical and economic comparison of epoetin alfa and darbepoetin alfa
Current Medical Research and Opinion, 2004The pharmacoeconomics of erythropoietic therapy for the treatment of anemia is receiving renewed attention due to the current availability of two agents. Epoetin alfa has been the standard of therapy for patients with renal disease and cancer-related anemia for more than a decade.
Anthony, Morreale +4 more
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