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Experimental characterization and numerical modeling of the fracture process in banded Alfas porous stone

open access: yesMaterial Design and Processing Communications, 2021
Summarization: The Alfas porous stone (porolithos) excavated in Rethimnon, Crete, Greece, often features two material bands with similar mineralogical but different depositional characteristics and therefore different mechanical parameters.
Pavlos Nomikos   +2 more
exaly   +2 more sources

Investigation of the size effect and the fracture process on the uniaxial compressive strength of the banded Alfas porous stone

open access: yesProcedia Structural Integrity, 2020
Summarization: This paper focuses on the experimental and numerical investigation of the size effect and the fracture process on the uniaxial compression strength (UCS) of the banded Alfas porous stone.
K Kaklis, Zach Agioutantis
exaly   +2 more sources
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Lutropin Alfa

Drugs, 2008
Lutropin alfa is the first and only recombinant human form of luteinizing hormone (LH) developed for use in the stimulation of follicular development. Dose-finding studies revealed a significant dose-dependent increase in the rate of optimal follicular development among women with hypogonadotropic hypogonadism and profound LH deficiency (or=35 years ...
Sohita, Dhillon, Gillian M, Keating
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Darbepoetin Alfa

Drugs, 2001
Darbepoetin alfa is a novel erythropoiesis-stimulating protein developed for the treatment of anaemia associated with chronic kidney disease. In single-dose studies in patients undergoing dialysis, the mean terminal half-life for intravenous darbepoetin alfa was approximately 3-fold longer than for intravenous recombinant human erythropoitin (r-HuEPO ...
T, Ibbotson, K L, Goa
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Drotrecogin alfa

Drugs of Today, 2004
Drotrecogin alfa (activated) is a human recombinant protein that is intravenously administered in a continuous, weight-based dose for patients with severe sepsis. In patients with severe sepsis, thrombin has been implicated in the interrelationship between the coagulation and inflammation pathways.
Michael J, Raggio, Peter E, Morris
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Elosulfase alfa

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Mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome, is an inherited, lysosomal storage disorder caused by genetic mutations in N-acetylgalactosamine-6-sulfatase (GALNS) enzyme gene. GALNS is essential for breakdown of glycosaminoglycans.
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Clinical and economic comparison of epoetin alfa and darbepoetin alfa

Current Medical Research and Opinion, 2004
The pharmacoeconomics of erythropoietic therapy for the treatment of anemia is receiving renewed attention due to the current availability of two agents. Epoetin alfa has been the standard of therapy for patients with renal disease and cancer-related anemia for more than a decade.
Anthony, Morreale   +4 more
openaire   +2 more sources

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