Results 21 to 30 of about 256,935 (224)
NUT midline carcinoma is an aggressive neoplasm defined by chromosomal rearrangements of the nuclear protein in testis (NUT) gene ( NUTM1 ). In this article, we present a strategy to detect this rare tumor through a standard DNA methylation array ...
S. Haefliger +6 more
semanticscholar +1 more source
Introducción: Los pacientes con cardiopatía congénita cianosante ductus dependiente, requieren de su permeabilidad para garantizar el flujo al sistema pulmonar o al sistémico.
Juan P. Rojas +2 more
doaj +3 more sources
Abstract Background Autoimmune diseases (AD) are severe pathophysiological ailments that are stimulated by an exaggerated immunogenic response towards self‐antigens, which can cause systemic or site‐specific organ damage. An array of complex genetic and epigenetic facets majorly contributes to the progression of AD, thus providing significant insight ...
Sagnik Nag +15 more
wiley +1 more source
Transmitted drug resistance to antiretroviral drugs in Spain during the period 2019–2021
Abstract To evaluate the prevalence of transmitted drug resistance (TDR) to nucleoside and nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and integrase strand transfer inhibitors (INSTI) in Spain during the period 2019–2021, as well as to evaluate transmitted clinically relevant resistance (TCRR) to ...
Laura Viñuela +27 more
wiley +1 more source
Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degeneration
Main Points Abundance and activity of Orai1 channel are increased in Retinal degeneration 10 (rd10) mice. Store‐operated calcium entry is deranged in oxidative stressed rat Müller glial cells. SOCE inhibition by 2‐Aminoethoxydiphenyl borate (2‐APB) rescues photoreceptors in degenerated retinas.
Basma Sukkar +9 more
wiley +1 more source
Abstract According to the World Health Organization (WHO), obesity and overweight have reached epidemic proportions globally. In Spain, the prevalence of obesity is high, especially in childhood, with an upward trend in the last two decades. While improving dietary habits and increasing physical activity has been the main focus on reducing obesity, its
Ana María Rivas Velasco +7 more
wiley +1 more source
Clustering algorithms such as k-means depend heavily on choosing an appropriate distance metric that reflect accurately the object proximities. A wide range of dissimilarities may be defined that often lead to different clustering results.
Manuel Martín Merino +4 more
doaj +1 more source
Tres dramaturgos en busca de universalidad: Buero Vallejo, Alfonso Sastre y Fernando Arrabal [PDF]
[No abstract]
openaire +3 more sources
Introduction Patients with cancer (PC) are at high risk of acquiring COVID-19 and can develop more serious complications. Deeper understanding of vaccines immunogenicity in this population is crucial for adequately planning vaccines programs. The ONCOVac
A. Cortés +26 more
semanticscholar +1 more source
El Desafío del "Orden Global" en Evolución
Estamos siendo testigos de un mundo que ya no gira en torno a la región euroatlántica, sino que se caracteriza cada vez más por el ascenso estratégico de China y la creciente importancia del Indo-Pacífico.
Alfonso Insuasty Rodríguez +6 more
doaj +1 more source

