Results 21 to 30 of about 256,935 (224)

NUT midline carcinomas and their differentials by a single molecular profiling method: a new promising diagnostic strategy illustrated by a case report

open access: yesVirchows Archiv, 2020
NUT midline carcinoma is an aggressive neoplasm defined by chromosomal rearrangements of the nuclear protein in testis (NUT) gene ( NUTM1 ). In this article, we present a strategy to detect this rare tumor through a standard DNA methylation array ...
S. Haefliger   +6 more
semanticscholar   +1 more source

Implantación de stent en neonatos y lactantes menores con cardiopatía congénita cianosante ductus dependiente

open access: yesRevista Colombiana de Cardiología, 2014
Introducción: Los pacientes con cardiopatía congénita cianosante ductus dependiente, requieren de su permeabilidad para garantizar el flujo al sistema pulmonar o al sistémico.
Juan P. Rojas   +2 more
doaj   +3 more sources

Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review

open access: yesImmunity, Inflammation and Disease, Volume 11, Issue 12, December 2023., 2023
Abstract Background Autoimmune diseases (AD) are severe pathophysiological ailments that are stimulated by an exaggerated immunogenic response towards self‐antigens, which can cause systemic or site‐specific organ damage. An array of complex genetic and epigenetic facets majorly contributes to the progression of AD, thus providing significant insight ...
Sagnik Nag   +15 more
wiley   +1 more source

Transmitted drug resistance to antiretroviral drugs in Spain during the period 2019–2021

open access: yesJournal of Medical Virology, Volume 95, Issue 12, December 2023., 2023
Abstract To evaluate the prevalence of transmitted drug resistance (TDR) to nucleoside and nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and integrase strand transfer inhibitors (INSTI) in Spain during the period 2019–2021, as well as to evaluate transmitted clinically relevant resistance (TCRR) to ...
Laura Viñuela   +27 more
wiley   +1 more source

Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degeneration

open access: yesGlia, Volume 71, Issue 11, Page 2511-2526, November 2023., 2023
Main Points Abundance and activity of Orai1 channel are increased in Retinal degeneration 10 (rd10) mice. Store‐operated calcium entry is deranged in oxidative stressed rat Müller glial cells. SOCE inhibition by 2‐Aminoethoxydiphenyl borate (2‐APB) rescues photoreceptors in degenerated retinas.
Basma Sukkar   +9 more
wiley   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the available evidence in relation to the potential obesogenic activity of certain chemical compounds that may be present in foods

open access: yesFood Risk Assess Europe, Volume 1, Issue 2, September‐December 2023., 2023
Abstract According to the World Health Organization (WHO), obesity and overweight have reached epidemic proportions globally. In Spain, the prevalence of obesity is high, especially in childhood, with an upward trend in the last two decades. While improving dietary habits and increasing physical activity has been the main focus on reducing obesity, its
Ana María Rivas Velasco   +7 more
wiley   +1 more source

A Clustering Algorithm Based on an Ensemble of Dissimilarities: An Application in the Bioinformatics Domain.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2022
Clustering algorithms such as k-means depend heavily on choosing an appropriate distance metric that reflect accurately the object proximities. A wide range of dissimilarities may be defined that often lead to different clustering results.
Manuel Martín Merino   +4 more
doaj   +1 more source

Limited T cell response to SARS-CoV-2 mRNA vaccine among patients with cancer receiving different cancer treatments

open access: yesEuropean Journal of Cancer, 2022
Introduction Patients with cancer (PC) are at high risk of acquiring COVID-19 and can develop more serious complications. Deeper understanding of vaccines immunogenicity in this population is crucial for adequately planning vaccines programs. The ONCOVac
A. Cortés   +26 more
semanticscholar   +1 more source

El Desafío del "Orden Global" en Evolución

open access: yesRevista Kavilando, 2023
Estamos siendo testigos de un mundo que ya no gira en torno a la región euroatlántica, sino que se caracteriza cada vez más por el ascenso estratégico de China y la creciente importancia del Indo-Pacífico.
Alfonso Insuasty Rodríguez   +6 more
doaj   +1 more source

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