Results 191 to 200 of about 249,441 (287)

Clinical Application of 4D Flow Cardiac Magnetic Resonance for Evaluating Complications After Surgical Aortic Valve Prosthesis Implantation. [PDF]

JACC Case Rep
López Alcolea J, Álvarez Vázquez A, Urmeneta Ulloa J, Cabrera JÁ, Forteza Gil A, Rivas Oyarzabal J, Recio Rodríguez M, Fernández Alfonso A, Cano Alonso R, Martínez de Vega V.   +9 more
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Mediastinal restaging in non-small cell lung cancer: comparing endobronchial ultrasound-guided transbronchial needle aspiration and mediastinal cryobiopsy following neoadjuvant therapy. [PDF]

Mediastinum
Ariza-Prota M, Pérez-Pallarés J, Alfonso LG, Angela LM, Torres-Rivas H, Fernández-Fernández L, González Gutiérrez MP, Berríos-Hernández M, García-Clemente M, López-González F.   +9 more
europepmc   +1 more source

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

ChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha, Sami A. Al‐Hussain, Basant Farag, AbdElAziz A. Nayl, Wesam Hussein, Abdelwahed R. Sayed, Magdi E. A. Zaki   +6 more
wiley   +1 more source

Recent Advances in 3D Bioprinting of Porous Scaffolds for Tissue Engineering: A Narrative and Critical Review. [PDF]

J Funct Biomater
Picado-Tejero D, Mendoza-Cerezo L, Rodríguez-Rego JM, Carrasco-Amador JP, Marcos-Romero AC.   +4 more
europepmc   +1 more source

The Accademia del Cimento and its European Context [PDF]

, 2010
Henry, John
core   +1 more source

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh, Alhasan Altayf, Ayham Qatza, Abubaker Alghazal, Hasan Al‐sakkaf, Muhammed Elhadi   +5 more
wiley   +1 more source

Mucoepidermoid Carcinoma of the Minor Salivary Glands Diagnosed by High-Definition Ultrasound and Fine-Needle Aspiration: A Milan System-Based Retrospective Study. [PDF]

Diagnostics (Basel)
Limongelli L, Forte M, Favia G, Dell'Olio F, Ingravallo G, Cascardi E, Maiorano E, Manfuso A, Copelli C, d'Amati A, Capodiferro S.   +10 more
europepmc   +1 more source

Integrating indigenous crops in agroforestry systems: Lesser yam and teak mixed systems are more profitable than monocultures in Indonesia

PLANTS, PEOPLE, PLANET, EarlyView.
Major staple crops are often introduced and cultivated in monocultures. Yams are staple crops native to the majority of low‐ and middle‐income countries and can provide an alternative to introduced staple crops. We showed that lesser yams cultivated together with teak trees (planted at the border of the farm) are more profitable than lesser yam ...
Budiadi, Sawitri, Enggal Primananda, Aqmal Nur Jihad, Marco Campera, Rika Bela Rahmawati   +5 more
wiley   +1 more source

Chronic cyclic mild heat stress downregulates genes encoding muscle structural components, contributing to reduced breast muscle mass in broiler chickens with minimal impact on meat quality. [PDF]

J Anim Sci
Achour A, Yehia M, Alfonso-Avila AR, Allard Prus JM, Ouellet V, Alnahhas N.   +5 more
europepmc   +1 more source