A trained communication partner's use of responsive strategies in aided communication with three adults with Rett syndrome: A case report. [PDF]
Wandin H, Lindberg P, Sonnander K.
europepmc +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source
I submit herewith the annual report from the Agricultural and Forestry Experiment Station, School of Natural Resources and Agricultural Sciences, University of Alaska Fairbanks, for the period ending December 31, 2009.
core
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado+4 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó+7 more
wiley +1 more source
Rhetoric vs. Reality: Paid Family and Medical Leave - Proposed Business Tax Credits and Pregnancy 401(K)s Fall Short for Working Families [PDF]
Access to comprehensive paid family and medical leave strengthens all American families because everyone potentially needs to take off from work at some point to recover from an illness, care for a family member, or welcome a new child.
Sarah Jane Glynn, Sunny Frothingham
core
Neighborhood Poverty and Household Financial Security [PDF]
In a previous study, The Pew Charitable Trusts examined the effects of neighborhood context on American families' economic mobility. That analysis found that neighborhood poverty is associated with downward mobility, reinforcing other research that has ...
Clinton Key+7 more
core
Application of team science best practices to the project management of a large, multi-site lung cancer screening research consortium. [PDF]
Steiner JS+17 more
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
BDP/FF NEXThaler to Improve Asthma Control Status in the Real World: The NEWTON Study. [PDF]
Braido F+6 more
europepmc +1 more source