Results 51 to 60 of about 823 (251)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Alfresco en el proceso de gestión documentaria en la Universidad César Vallejo sede Lima norte 2017 [PDF]

open access: yes, 2017
La presente tesis se encuentra dentro de la línea de investigación Sistemas basados en gestión de proceso de negocios se orientó en la aplicación del software Alfresco en el proceso de gestión documentaria en la Universidad César Vallejo sede Lima norte ...
Preciado Farías, Luis Alberto
core  

Deep Learning-Based Defect Prediction for Mobile Applications. [PDF]

open access: yesSensors (Basel), 2022
Jorayeva M   +3 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Professional Alfresco: Practical Solutions for Enterprise Content Management

open access: yes, 2010
A timely and authoritative guide, written by the Chief Architect and Founder of Alfresco. Alfresco is considered the leading open source solution for Web and Content Management.
Farman, Mike   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Contextual heuristics : usability evaluation of Alfresco

open access: yes, 2015
Syftet med detta examensarbete att undersöka om systemsuiten Alfresco uppfyller krav på användbarhet för dokumenthantering och samarbete i interaktiva miljöer.
Anagrius, Jimmy
core  

Alfresco - Documenta: gestión compartida de contenidos

open access: yes, 2011
Peer ...
Román-Molina, Juan, Ríos, Yolanda
openaire   +2 more sources

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