Results 81 to 90 of about 398,973 (330)

Drug Resistance Predictions Based on a Directed Flag Transformer

Advanced Science, EarlyView.
 CAPTURE, a deep learning framework combining structural and sequence data to predict drug‐resistant Mpro mutations, revealing that PAXLOVID use may be accelerating resistance—supporting real‐time viral surveillance and therapeutic design. Abstract The evolving SARS‐CoV‐2 virus threatens global public health, particularly with potential resistance to ...
Dong Chen, Gengzhuo Liu, Hongyan Du, Benjamin Jones, Junjie Wee, Rui Wang, Jiahui Chen, Jana Shen, Guo‐Wei Wei   +8 more
wiley   +1 more source

A Systematic Computational Framework for Practical Identifiability Analysis in Mathematical Models Arising from Biology

Advanced Science, EarlyView.
A systematic computational framework is developed for practical identifiability analysis in biological models. The framework establishes a rigorous definition, introduces efficient coordinate‐based identifiability metrics, and proposes novel regularization strategies.
Shun Wang, Wenrui Hao
wiley   +1 more source

Junction Type Representations of the Temperley-Lieb Algebra and Associated Symmetries

Symmetry, Integrability and Geometry: Methods and Applications, 2010
Inspired by earlier works on representations of the Temperley-Lieb algebra we introduce a novel family of representations of the algebra. This may be seen as a generalization of the so called asymmetric twin representation.
Anastasia Doikou, Nikos Karaiskos
doaj   +1 more source

Hybrid rule‐based and optimization‐driven framework for the synthesis of end‐to‐end optimal pharmaceutical processes

AIChE Journal, EarlyView.
Abstract The modernization of pharmaceutical manufacturing is driving a shift from traditional batch processing to continuous alternatives. Synthesizing end‐to‐end optimal (E2EO) manufacturing routes is crucial for the pharmaceutical industry, especially when considering multiple operating modes—such as batch, continuous, or hybrid (containing both ...
Yash Barhate, Daniel J. Laky, Daniel Casas‐Orozco, Gintaras V. Reklaitis, Zoltan K. Nagy   +4 more
wiley   +1 more source

On Representations of sl(n, C) Compatible with a Z2-grading

Acta Polytechnica, 2010
This paper extends existing Lie algebra representation theory related to Lie algebra gradings. The notion of a representation compatible with a given grading is applied to finite-dimensional representations of sl(n,C) in relation to its Z2-gradings.
M. Havlíček, E. Pelantová, J. Tolar
doaj  

Ring homomorphisms on real Banach algebras

International Journal of Mathematics and Mathematical Sciences, 2003
Let B be a strictly real commutative real Banach algebra with the carrier space ΦB. If A is a commutative real Banach algebra, then we give a representation of a ring homomorphism ρ:A→B, which needs not be linear nor continuous.
Takeshi Miura, Sin-Ei Takahasi
doaj   +1 more source

Coherent states for a quantum particle on a circle

, 1998
The coherent states for the quantum particle on the circle are introduced. The Bargmann representation within the actual treatment provides the representation of the algebra $[\hat J,U]=U$, where $U$ is unitary, which is a direct consequence of the ...
Ali M K, Bargmann V, Barut A O, Bogoliubov N N, Celeghini E, De Bièvre S, DeWitt-Morette C, Emch G G, Isham C J, J Rembielinski, K Kowalski, L C Papaloucas, Louisell W H, Perelomov A M, Pradhan T, Rideau G, Whittaker E T, Woronowicz S L   +17 more
core   +1 more source

Mapping uncertainty using differentiable programming

AIChE Journal, EarlyView.
Abstract Uncertainty quantification (UQ) and propagation is a ubiquitous challenge in science, permeating our field in a general fashion, and its importance cannot be overstated. Recently, the commoditization of differentiable programming, motivated by the development of machine learning, has allowed easier access to tools for evaluating derivatives of
Victor Alves, Carl D. Laird, Fernando V. Lima, John R. Kitchin   +3 more
wiley   +1 more source

Multinomial fix-Mahonian statistics [PDF]

Surveys in Mathematics and its Applications
The permutation statistics fix, des, maj, and inv have different original contexts, and appear in diverse scientific domains such as probability, physics, and genomics.
Hery Randriamaro
doaj  

Minimum reflux calculation for multicomponent distillation in multi‐feed, multi‐product columns: Algorithms and examples

AIChE Journal, EarlyView.
Abstract In this work, we present the first algorithm for identifying the minimum reboiler vapor duty requirement for a general multi‐feed, multi‐product (MFMP) distillation column separating ideal multicomponent mixtures. This algorithm incorporates our recently developed shortcut model for MFMP columns.
Zheyu Jiang, Mohit Tawarmalani, Rakesh Agrawal   +2 more
wiley   +1 more source