Results 171 to 180 of about 11,243,181 (388)
An Algorithm for the Determination of the Polynomial of Best Minimax Approximation to a Function Defined on a Finite Point Set [PDF]
, 1959 Philip C. Curtis, Werner L. Frank
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Proceedings of the forty-third annual ACM symposium on Theory of computing, 2011 We revisit classic algorithmic search and optimization problems from the perspective of competition. Rather than a single optimizer minimizing expected cost, we consider a zero-sum game in which an optimization problem is presented to two players, whose only goal is to outperform the opponent. Such games are typically exponentially large zero-sum games,
Immorlica, Nicole +5 more
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Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
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Euclid's algorithm in cubic fields of negative discriminant [PDF]
, 1951 H. Davenport
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Permutation Generation: Two New Permutation Algorithms [PDF]
arXiv, 2003 Two completely new algorithms for generating permutations, shift-cursor algorithm and level algorithm, and their efficient implementations are presented in this paper. One implementation of the shift cursor algorithm gives an optimal solution of the permutation generation problem, and one implementation of the level algorithm can be used to generate ...
arxiv
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
An algorithm for the determination of the polynomial of best minimax approximation to a function defined on a finite point set [PDF]
, 1958 Philip C. Curtis, Werner L. Frank
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The presented material constitutes an integral part of the work entitled "The Formula of Metamorphosis," included in the volume "Metamorphosis." This work analyzes not only fundamental mathematical concepts but also the color palette used in algorithmic formulas.
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