Results 211 to 220 of about 11,243,181 (388)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

SDE-based software reliability additive models with masked data using ELS algorithm

open access: yesJournal of King Saud University: Computer and Information Sciences
The growing complexity of contemporary software systems, with multiple sub-modules, demands innovative modeling approaches, especially in addressing intricate failures and masked data generation.
Jianfeng Yang   +4 more
doaj  

Message passing variational autoregressive network for solving intractable Ising models

open access: yesCommunications Physics
Deep neural networks have been used to solve Ising models, including autoregressive neural networks, convolutional neural networks, recurrent neural networks, and graph neural networks.
Qunlong Ma   +4 more
doaj   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

open access: yesFEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones   +2 more
wiley   +1 more source

Handling Optimization under Uncertainty Problem Using Robust Counterpart Methodology

open access: yesJurnal Teknik Industri, 2013
In this paper we discuss the robust counterpart (RC) methodology to handle the optimization under uncertainty problem as proposed by Ben-Tal and Nemirovskii.
Diah Chaerani, Cornelis Roos
doaj  

Browder spectra of closed upper triangular operator matrices

open access: yesAIMS Mathematics
Let $ T_{B} = \left[\begin{array}{ll} A & B \\ 0 & D \end{array}\right] $ be an unbounded upper operator matrix with diagonal domain, acting in $ \mathcal H \oplus\mathcal K $, where $ \mathcal H $ and $ \mathcal K $ are Hilbert spaces.
Qingmei Bai   +2 more
doaj   +1 more source

The Lawson algorithm and extensions [PDF]

open access: bronze, 1968
John R. Rice, Karl H. Usow
openalex   +1 more source

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