Results 41 to 50 of about 6,238,484 (290)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Algorithm Instance Games [PDF]
, 2014 This paper introduces algorithm instance games (AIGs) as a conceptual classification applying to games in which outcomes are resolved from joint strategies algorithmically.
Johnson, Samuel D., Lu, Tsai-Ching
core
, 2012 We propose a simple distributed algorithm for balancing indivisible tokens on graphs. The algorithm is completely deterministic, though it tries to imitate (and enhance) a random algorithm by keeping the accumulated rounding errors as small as possible.
Lovász L. +5 more
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Postmortem Analysis of Decayed Online Social Communities: Cascade Pattern Analysis and Prediction
Complexity, 2018 Recently, many online social networks, such as MySpace, Orkut, and Friendster, have faced inactivity decay of their members, which contributed to the collapse of these networks.
Mohammed Abufouda
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
, 2012 In terms of the concepts of state and state transition, a new heuristic random search algorithm named state transition algorithm is proposed. For continuous function optimization problems, four special transformation operators called rotation ...
A. H. Wright +33 more
core +1 more source
Weed Identification Using Deep Learning and Image Processing in Vegetable Plantation
IEEE Access, 2021 Weed identification in vegetable plantation is more challenging than crop weed identification due to their random plant spacing. So far, little work has been found on identifying weeds in vegetable plantation.
Xiaojun Jin, Jun Che, Yong Chen
doaj +1 more source
Transactions of the American Mathematical Society, 1992 We consider the state of elementary recursion theory when the familiar 0 , 1 , + , × , = , > 0, 1, +, \times , =, > of ordinary arithmetic are replaced by constants, functions, and relations from an arbitrary model.
Friedman, Harvey, Mansfield, Richard
openaire +2 more sources