Results 51 to 60 of about 225,922 (311)

Algorithms and Data Structures for Sparse Polynomial Arithmetic

open access: yesMathematics, 2019
We provide a comprehensive presentation of algorithms, data structures, and implementation techniques for high-performance sparse multivariate polynomial arithmetic over the integers and rational numbers as implemented in the freely available Basic ...
Mohammadali Asadi   +3 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Web-Based Questionnaires for Type Theory Course [PDF]

open access: yesActa Electrotechnica et Informatica, 2017
This paper describes our effort on the usage of modern information and communication technologies as well as innovation process in the field of teaching.
Daniel MIHÁLYI   +3 more
doaj   +1 more source

Data Structures and Algorithms for k-th Nearest Neighbours Conformational Entropy Estimation

open access: yesBiophysica, 2022
Entropy of multivariate distributions may be estimated based on the distances of nearest neighbours from each sample from a statistical ensemble. This technique has been applied on biomolecular systems for estimating both conformational and translational/
Roberto Borelli   +2 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Data structures and compression algorithms for high-throughput sequencing technologies

open access: yesBMC Bioinformatics, 2010
Background High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively short nucleotide sequences, in applications ranging from genome sequencing ...
Christley Scott   +4 more
doaj   +1 more source

Efficient and Modular Coalgebraic Partition Refinement [PDF]

open access: yesLogical Methods in Computer Science, 2020
We present a generic partition refinement algorithm that quotients coalgebraic systems by behavioural equivalence, an important task in system analysis and verification.
Thorsten Wißmann   +3 more
doaj   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy