Results 21 to 30 of about 1,008,443 (223)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Secure Source Coding with a Helper
, 2012 We consider a secure source coding problem with a rate-limited helper. In particular, Alice observes an independent and identically distributed (i.i.d.) source X and wishes to transmit this source losslessly to Bob over a rate-limited link.
Ramchandran, Kannan +2 more
core +2 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Between, 2012 Lo scopo di questo saggio è quello di presentare un ‘case study’ finora inesplorato nel campo degli studi sugli adattamenti: la danza in Alice’s Adventures in Wonderland (1865) di Lewis Carroll e le sue trasformazioni in sede di transmodalizzazione. In particolar modo si prenderanno in esame i due adattamenti cinematografici più celebri del romanzo ...
openaire +4 more sources
EPJ Web of Conferences, 2013 While groundbreaking measurements on the properties of strongly interacting matter in p+p, p+Aand A+A collisions at the LHC are being performed, it is clear that many important questions in heavy-ion physics will remain unanswered in this first phase of beam times up to 2017.
openaire +3 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Overview of ALICE Results at Quark Matter 2014
, 2014 The results released by the ALICE collaboration at Quark Matter 2014 address topics from identified-particle jet fragmentation functions in pp collisions, to the search for collective signatures in p-Pb collisions to precision measurements of jet ...
Grosse-Oetringhaus, Jan Fiete
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
A secure additive protocol for card players [PDF]
, 2011 Consider three players Alice, Bob and Cath who hold a, b and c cards, respectively, from a deck of d=a+b+c cards. The cards are all different and players only know their own cards.
Cordon-Franco, Andres +4 more
core +2 more sources