Results 101 to 110 of about 76,934 (296)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The Creolizing Genre of SF and the Nightmare of Whiteness in John W. Campbell's "Who Goes There?"
Journal of Science Fiction and Philosophy, 2018 The alien in science fiction has not often been seen as part of an imperial colonial discourse. By examining John W. Campbell’s founding golden age SF text, “Who Goes There?” (1938), this paper explores the ways in which the alien adheres to an invisible
Bernabe S. Mendoza
doaj
Crustacean species off the coast of Kıyıköy (Black Sea, Türkiye) with a new record
Oceanological and Hydrobiological StudiesExamination of hard- and soft-bottom samples collected off the coast of Kıyıköy (Black Sea, Türkiye) using grabs, quadrats and trawls revealed a total of 39 crustaceans belonging to eight orders.
Özgen Özge, Açık Şermin
doaj +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The death of own and the death of alien in Gogol' story "Taras Bul'ba"
Opera slavicaThe article examines the features of the depiction of the death of characters in Gogol's story "Taras Bulba”. The main attention is paid to the relationship between spatial spheres, one of which includes Orthodox Cossacks, and the other Catholic Poles ...
Vladislav Šajevič Krivonos
doaj +1 more source
The ecosystem resilience approach to control the invasive alien species Australian swamp stonecrop (Crassula helmsii) [PDF]
, 2022 Janneke M. M. van der Loop +4 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Alienated History, Alien Events
ProblemosHuman history is largely shaped by human actions – most historical events are man-made, despite nature also playing a role. Yet, people often see these events as alien, as if shaped by something or someone else. For instance, many view man-made climate change as unrelated to humanity, while non-deniers often see no way to influence it collectively ...
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source