Results 61 to 70 of about 76,934 (296)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Monstruos, aliens y zombis: figuraciones de la alteridad en clave semiótica
Forma y FunciónLa presente investigación explora las representaciones contemporáneas de monstruos, aliens y zombis como manifestaciones del imaginario actual que exploran diferentes formas de alteridad.
Carlos Andrés Arango-Lopera +2 more
doaj +1 more source
Papers and proceedings of the Royal Society of Tasmania, 1877 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Opinion The “Non-Native” Enigma
Human-Wildlife Interactions, 2017 Non-native species have been introduced to ecosystems throughout the world, and in some instances, have degraded the invaded system. Consequently, the distinction between native and non-native species has become an integral component of conservation ...
Danny Caudill, Gretchen Caudill
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
On Darwin’s Steps: Citizen Science Can Help Keep an Eye on Alien Species [PDF]
, 2021 Ioannis Giovos +5 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
How Alien Can Alien Worlds Be?
, 2017 {"references": ["Adibekyan, V. 2017, In Astronomical Society of the Pacific Conference Series, edited by A. M. Mickaelian, H. A. Harutyunian, & E. H. Nikoghosyan, Astronomical Society of the Pacific Conference Series, vol. 511, p. 70.", "Adibekyan, V., Figueira, P., & Santos, N. C. 2016, Origins of Life and Evolution of the Biosphere, 46, 351.",
Adibekyan, V. +2 more
openaire +2 more sources