Results 201 to 210 of about 1,546,431 (297)

Supermeres Containing the Discoidin Domain Receptor 1 Extracellular Domain Promote Collagen Alignment and Immune Exclusion in Microsatellite-Stable Colorectal Cancer. [PDF]

Cancer Res Commun
Hamilton MS, Ellis ST, Cao Z, Tutanov OS, Simmons AJ, Aramandla R, Higginbotham JN, Ramirez M, Schnee KW, Bechard ME, Kaur H, Franklin JL, Mandal S, Lau KS, Liu Q, Goettel JA, Pozzi A, Coffey RJ.   +17 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Alignment Kernels Based on a Generalization of Alignments

IEICE Transactions on Information and Systems, 2014
openaire   +3 more sources

scGSI: Graph-guided self-supervised integration of paired single-cell multi-omics. [PDF]

PLoS Comput Biol
Chen X, Yang Z, Liu X, Xie Z, Guo W.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Phylogenomic subsampling and upsampling for efficient evolutionary analyses of big data. [PDF]

Mol Biol Evol
Kumar S, Tamura K, Sharma S.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Letter to the Editor: Clinical Outcomes and Mechanical Complications After Adult Spinal Deformity Surgery in Patients Aged 80 Years or Older: A Propensity Score-Matched Comparative Study. [PDF]

Global Spine J
Wang L.
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Robotic-assisted total knee arthroplasty: accuracy, clinical outcomes, complications, learning curve and cost-effectiveness: a critical clinical review. [PDF]

J Robot Surg
Szymczak J, Łapiński M, Stolarczyk A, Balawender K.   +3 more
europepmc   +1 more source