Results 41 to 50 of about 1,016,136 (269)
Swapping Metagenomics Preprocessing Pipeline Components Offers Speed and Sensitivity Increases
mSystems, 2022 Increasing data volumes on high-throughput sequencing instruments such as the NovaSeq 6000 leads to long computational bottlenecks for common metagenomics data preprocessing tasks such as adaptor and primer trimming and host removal.
George Armstrong +21 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Aligners: Decoupling LLMs and Alignment
Findings of the Association for Computational Linguistics: EMNLP 2024Large Language Models (LLMs) need to be aligned with human expectations to ensure their safety and utility in most applications. Alignment is challenging, costly, and needs to be repeated for every LLM and alignment criterion. We propose to decouple LLMs and alignment by training aligner models that can be used to align any LLM for a given criteria on ...
Lilian Ngweta +5 more
openaire +3 more sources
The Relevant Approaches for Aligning Carbon Nanotubes
Micromachines, 2022 Carbon-nanotube (CNT) is a promising material owing to its compelling mechanical, thermal and electrical properties and has been applied in a broad variety of fields such as composite, fiber, film and microelectronic.
Zhifu Yin +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
Joint Prediction of Word Alignment with Alignment Types [PDF]
Transactions of the Association for Computational Linguistics, 2017 Current word alignment models do not distinguish between different types of alignment links. In this paper, we provide a new probabilistic model for word alignment where word alignments are associated with linguistically motivated alignment types. We propose a novel task of joint prediction of word alignment and alignment types and propose novel semi ...
Anahita Mansouri Bigvand +2 more
openaire +2 more sources
Aligning best practices to develop targeted critical thinking skills and habits
Journal of the Scholarship of Teaching and Learning, 2017 This project evaluated the effectiveness of a course design within an upper-level biology course that incorporated what prior scholarship of teaching and learning (SoTL) research has suggested to be best practices for developing critical thinking skills ...
Ilea Eskildsen Heft, Lauren F V Scharff
doaj +1 more source