Results 151 to 160 of about 113,730 (289)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Correction: Recent population history in Swedish cattle breeds. [PDF]

Genet Sel Evol
Adepoju D, Ohlsson JI, Klingström T, Rius-Vilarrasa E, Johansson AM, Johnsson M.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The Systemic Connection in Dental Erosion: A Cross-Sectional Analysis of the Interrelationship Between General Health Status and Alimentation Patterns. [PDF]

Medicina (Kaunas)
Iacob S, Bălaj M, Chisnoiu R, Chisnoiu AM, Iosa A, Păstrav M, Buduru S, Kui A.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Religions et alimentation

, 2017
Colloque international Religions et alimentation. Normes alimentaires, organisation sociale et représentations du monde, BNU, Strasbourg, 11-13 octobre 2017 (programme)
A.-L. Zwilling
core  

Introduction au dossier

Mondes du Tourisme, 2013
Cécile Clergeau, Olivier Etcheverria
doaj  

New hybrid sequencing data of <i>Vreelandella sulfidaeris</i> DSM 15722^T and <i>Vreelandella aquamarina</i> DSM 15723 provide circular and complete genomes. [PDF]

Data Brief
Marquet G, Renault M, Irlinger F, Hervé V.   +3 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Protéines végétales et alimentation durable

, 2018
Protéines végétales et alimentation durable.
Salles, Jérôme, Laleg, Karima, Gueugneau, Marine, Berrazaga, Insaf, Lebecque, Patrice, Giraudet, Christophe, Rigaudière, Jean-Paul, Walrand, Stephane, Patrac, Véronique, Jouve, Chrystele   +9 more
core