Results 141 to 150 of about 30,414 (192)

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu   +13 more
wiley   +1 more source

Genes Associated With Fracture Risk in Thoroughbred Horses Have Novel Roles in Osteogenesis

open access: yesAnimal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Bone fractures in Thoroughbred racehorses are a major welfare problem. Genetic factors contribute to fracture risk. Cell models have previously identified 112 differentially expressed genes in bone‐forming osteoblasts derived from horses at high and low genetic risk of fracture. However, 42 of these genes have no published role in bone.
Amy C. Ross   +5 more
wiley   +1 more source

The tiger salamander as a promising alternative model organism to the axolotl for fracture healing and regenerative biology research

open access: yesThe Anatomical Record, Volume 309, Issue 8, Page 2151-2175, August 2026.
Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley   +1 more source

IL‐6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA‐Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Purpose To investigate the expression profile of IL‐6 in patients with acute promyelocytic leukemia (APL) and its role in modulating the ability of hPMSCs to regulate the differentiation of NB4 cells. Methods Peripheral blood samples were obtained from newly diagnosed APL patients and healthy controls.
Rong Qi   +4 more
wiley   +1 more source

hUC‐MSCs via β‐NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2‐SARM1‐NF‐κB Signaling Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study found that human umbilical cord mesenchymal stem cells secrete β‐NGF, which binds to the TrkA receptor on neurons, upregulates the protein levels of STMN2 and NMNAT2 in mice with perioperative neurocognitive disorders, and thereby downregulates the protein levels of SARM1 and p‐NF‐κB.
Kai Wang   +9 more
wiley   +1 more source

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