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Thiophosphorylation of Alkaline Phosphatase
Nature New Biology, 1973ALKALINE phosphatase from Escherichia coli has been reported to be phosphorylated by a phosphate ester substrate1, a particular feature being that only one of two potentially active sites appeared to be phosphorylated at any one time. Binding studies with inorganic phosphate have shown there is one high affinity and a second low affinity site at pH 8 ...
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Alkaline Phosphatase: Structure, Expression and its Function in Bone Mineralization.
Gene, 2020S. Vimalraj
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The Serum Alkaline Phosphatase
JAMA: The Journal of the American Medical Association, 1968The alkaline phosphatases constitute a large group of enzymes of low specificity that are involved in the hydrolysis of phosphate monoesters at a pH of about 9. They also play important roles in the transport of sugar and phosphate in the intestinal mucosa, kidney tubule, placenta, and bones.
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Intestinal Alkaline Phosphatase-Like Properties of Horse Kidney Alkaline Phosphatase
Enzyme, 1983Two isoenzymes of alkaline phosphatase from horse kidney were identified by cellulose acetate electrophoresis. Horse kidney alkaline phosphatase was similar to horse intestinal alkaline phosphatase, in regard to both antigenicity and response to levamisole inhibition, but different from horse liver alkaline phosphatase.
Walter E. Hoffmann +2 more
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Alkaline Phosphatase and Hyperthyroidism
Annals of Internal Medicine, 1979Excerpt To the editor: Dr. Cooper and colleagues mention in their recent article "Alkaline Phosphatase Isoenzyme Patterns in Hyperthyroidism" in the February issue (1), that "bone healing in patien...
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Multisystemic Functions of Alkaline Phosphatases
2013Human and mouse alkaline phosphatases (AP) are encoded by a multigene family expressed ubiquitously in multiple tissues. Gene knockout (KO) findings have helped define some of the precise exocytic functions of individual isozymes in bone, teeth, the central nervous system, and in the gut.
René Buchet +2 more
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Assays for alkaline phosphatase activity: Progress and prospects
Trends in Analytical Chemistry (TrAC), 2019Zhenwei Tang +3 more
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Site of alkaline phosphatase attachment in alkaline phosphatase-immunoglobulin G complexes
Clinica Chimica Acta, 1981Sera containing the rare alkaline phosphatase-immunoglobulin G complex were studied to try to determine the type of interaction involved. Pepsin and papain digestion of immunoglobulin G showed that alkaline phosphatase was attached to the F(ab')2 region of the immunoglobulin molecule and not to the Fc region.
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