Results 71 to 80 of about 1,219,715 (347)

Association of intestinal alkaline phosphatase with necrotizing enterocolitis among premature infants [PDF]

open access: yes, 2019
Importance: Necrotizing enterocolitis (NEC) in preterm infants is an often-fatal gastrointestinal tract emergency. A robust NEC biomarker that is not confounded by sepsis could improve bedside management, lead to lower morbidity and mortality, and permit
Barkemeyer, Brian   +10 more
core   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

open access: yes, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique   +7 more
core   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

open access: yesAdvanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj   +10 more
wiley   +1 more source

Single-Molecule Analysis of Alkaline Phosphatase

open access: yesKinases and Phosphatases
Chemical studies usually consist of measurements made on large ensembles of molecules with data representing average values for the population. It has been shown that individual molecules of a given enzyme have different properties. Large-scale averaging
Douglas B. Craig
doaj   +1 more source

Regulated internalization of caveolae [PDF]

open access: yes, 1994
Caveolae are specialized invaginations of the plasma membrane which have been proposed to play a role in diverse cellular processes such as endocytosis and signal transduction.
Joggerst, B., Parton, R. G., Simons, K.
core   +4 more sources

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory   +3 more
wiley   +1 more source

Primate placental alkaline phosphatase [PDF]

open access: yesFEBS Letters, 1981
Volume 135, number 1 FEBS LETTERS November 1981 PRIMATE PLACENTAL ALKALINE PHOSPHATASE George J. DOELLGAST, Shirley C. WEI, Martha KENNEDY, Harold STILLS + and Kurt L. BENIRSCHKE* Department of Biochemistry, +Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC 27103 and *San Diego Zoo, La Jolla, CA, USA Received 5 ...
Doellgast, George J.   +4 more
openaire   +2 more sources

Alkaline phosphatase normalization is a biomarker of improved survival in primary sclerosing cholangitis

open access: yesAnnals of Hepatology, 2016
Introduction. Recent studies suggest that serum alkaline phosphatase may represent a prognostic biomarker in patients with primary sclerosing cholangitis. However, this association remains poorly understood.
Moira Hilscher   +4 more
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Alkaline phosphatase: Distinguishing between tuberculous and nontuberculous pleural effusion

open access: yesLung India, 2009
Objectives: To evaluate the value of pleural fluid alkaline phosphatase and pleural fluid/serum alkaline phosphatase ratio for the purpose of differentiating tuberculous from nontuberculous pleural effusion. Materials and Methods: A total of 60 indoor
Jadhav Ashish   +2 more
doaj  

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