Results 81 to 90 of about 116,300 (262)

Design, Synthesis, and Antifungal Activities of Phenylpyrrole Analogues Based on Alkaloid Lycogalic Acid

open access: yesMolecules
Plant diseases caused by pathogenic fungi seriously affect the yield and quality of crops, cause huge economic losses, and pose a considerable threat to global food security.
Shuaiheng Zhang   +3 more
doaj   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Aaptamine: A Versatile Marine Alkaloid for Antioxidant, Antibacterial, and Anticancer Therapeutics

open access: yesChemistry
Aaptamine (8,9-dimethoxy-1H-benzo[de][1,6]naphthyridine), an alkaloid obtained from marine sponges of the genus Aaptos (Demospongiae, Suberitida, Suberitidae), has attracted significant attention as a promising scaffold for the development of antioxidant,
Navin Kumar Tailor   +2 more
doaj   +1 more source

Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1

open access: yesEcoEnergy, EarlyView.
A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang   +9 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

N-Methoxycarbonyl-9,12-Dimethoxy-Norchelerythrine: A Novel Antifungal Type-III Benzo[c]phenanthridine from Zanthoxylum simulans Hance Seedlings

open access: yesMolbank
Zanthoxylum simulans Hance, commonly known as Sichuan pepper, is a well-known medicinal plant recognized for its potential as a source of bioactive specialized metabolites.
Diego Cárdenas-Laverde   +2 more
doaj   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

open access: yesELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

THE ERGOT ALKALOIDS

open access: yesJournal of Biological Chemistry, 1934
W A, Jacobs, L C, Craig
openaire   +2 more sources

Translocator protein positron emission tomography as a biomarker for posttraumatic epilepsy and behavioral comorbidities following traumatic brain injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar   +14 more
wiley   +1 more source

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