Results 151 to 160 of about 113,902 (309)

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

open access: yesAdvanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao   +21 more
wiley   +1 more source

From Yield to Flavor: The Role of Lipid Coatings in Beef Aging. [PDF]

open access: yesJ Food Sci
Rezende-de-Souza JH   +10 more
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

Time-Resolved Resonant Inelastic X-ray Scattering Reveals How Orbital Symmetry Alignment Enables C-H Activation. [PDF]

open access: yesJ Am Chem Soc
Dederichs T   +13 more
europepmc   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

Metabolic Specialization and Synergy in Alkane Degradation By a Microbial Consortium: An Integrated Genomic and Geochemical Approach. [PDF]

open access: yesCurr Microbiol
de Santana Nazaré PGB   +5 more
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

Contribution of cyanobacterial alkane production to the ocean hydrocarbon cycle

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
D. Lea-Smith   +9 more
semanticscholar   +1 more source

Impact of Small-Alkane Solvents on Polyolefin Hydrogenolysis over a Ruthenium Catalyst. [PDF]

open access: yesInd Eng Chem Res
Kots PA   +11 more
europepmc   +1 more source

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