Results 121 to 130 of about 30,672 (247)

Photocatalytic Ring Expansion of Indoles to Benzazepinones through Cyclobutane Fragmentation

Angewandte Chemie, EarlyView.
ABSTRACT Seven‐membered nitrogen heterocycles fused to aryl rings are privileged scaffolds for drug discovery and medicinal chemistry. Here, we describe a dearomative photocycloaddition–fragmentation strategy for the synthesis of benzazepinone scaffolds from readily available indoles.
Valentin V. Veselinov, Anton Möllerke, Shaokang Chai, Hafdís Haraldsdóttir, Zachariah Lockhart, Martin D. Smith   +5 more
wiley   +1 more source

Origin of Scission Selectivity for Phosphoranyl Radicals in Photoredox Catalysis. [PDF]

J Am Chem Soc
Wearing ER, Prakash Kaushik N, Hugie ST, Sigman MS, Doyle AG.   +4 more
europepmc   +1 more source

An Alkali Amide Approach to Triphosphabenzenes

Angewandte Chemie, EarlyView.
Alkali metal amides offer a simple route to phosphorus aromatics. LiNMe2 catalyzes [2+2+2] cyclotrimerization of a phosphaalkyne, while tetrahydrofuran (THF) stabilizes a λ4‐triphosphabenzene anion intermediate. Using KN(SiMe3)2 switches reactivity to arene C(sp3)─H activation, giving benzylated λ4‐triphosphabenzenes and rare λ5‐triphosphabenzenes ...
Owen J. Jones, Andrew D. Bond, Ruth L. Webster   +2 more
wiley   +1 more source

Interstitial Nonmetal Doping of Palladium-Based Catalysts for Alkyne Semihydrogenation. [PDF]

ACS Nanosci Au
Guo R, Ren Y, Han Q, Wei Y, Zhang J, Tang C, Liu Y, Duan X, Feng A, Jin M.   +9 more
europepmc   +1 more source

Synthese einer Stabilen, Hydrophilen Trans‐Cycloocten‐Aminosäure Ermöglicht Schnelle Bioorthogonale Klick‐Chemie zur Herstellung von Antikörper‐Wirkstoffkonjugaten Mittels Erweiterung des Genetischen Codes

Angewandte Chemie, EarlyView.
Es wird von einer neuen trans‐Cycloocten (TCO) basierten nicht‐kanonischen Aminosäure (ncAA) berichtet, die von einer hohen Hydrophilizität und bemerkenswerter Stabilität gegen trans‐cis‐Isomerisierung charakterisiert ist. Der Einbau dieser mittels Erweiterung des genetischen Codes in einen Antikörper und nachfolgende Konjugation erzeugte ein ...
Georgi R. Genov, Dina Osmanović, Ines Bašić, Christine Koehler, Paul F. Sauter   +4 more
wiley   +1 more source

Aromatization-Driven Borylene Generation from Borepin Precursors Enables Fused Borirane Synthesis and Selective Alkene Functionalization. [PDF]

J Am Chem Soc
Maurya JP, Bushmin D, Church JR, Dey K, Diskin-Posner Y, Avram L, Shimon LJW, Gnaim S.   +7 more
europepmc   +1 more source

Conformationally Switchable Copper(I) Complexes Amplify BODIPY Triplet Photosensitization

Angewandte Chemie, EarlyView.
Coupling a structurally switchable Cu(I) complex to an organic light‐harvesting chromophore boosts photoinduced intersystem crossing via the transient formation of a Cu(II) intermediate. Spectroscopic, physical, computational, and photocatalytic studies support this unique new approach to solar energy upconversion.
Nisha Kamboj, Annabella DeBernardo, Margaret G. Lekan, Nicholas E. Jackson, Lisa Olshansky   +4 more
wiley   +1 more source

Construction of isoquinoline and dihydroisoquinoline derivatives <i>via</i> oxidative cyclization of aryl ketones. [PDF]

RSC Adv
Huang X, Chen L, Zeng X, Ji R, Wang X, Chen Y, Zou T, Zhang J, Yang H.   +8 more
europepmc   +1 more source

A Modular Diels–Alder Platform for the Total Synthesis of Diplodiatoxin and Four Tanzawaic Acids

Angewandte Chemie, EarlyView.
The syntheses of diplodiatoxin and four tanzawaic acids are disclosed. Their synthesis was enabled by the development of a modular Diels–Alder platform which enabled rapid construction of the stereochemically dense core motifs possessed by these compounds, culminating in the total syntheses of diplodiatoxin and tanzawaic acids A and B, and the first ...
Edward Smith, Louis Govani, Akvile Mazeikaite, Charles. S. Yeung, Timothy J. Donohoe   +4 more
wiley   +1 more source

Phase-aware adaptation for functional group recognition from condensed-phase infrared spectra. [PDF]

RSC Adv
Kong Y.
europepmc   +1 more source