Results 181 to 190 of about 4,043,885 (307)

Effect of right ventricular free wall longitudinal strain on all-cause death in patients with isolated severe tricuspid regurgitation and atrial fibrillation. [PDF]

Front Cardiovasc Med, 2023
Ogawa M, Kuwajima K, Yamane T, Hasegawa H, Yagi N, Shiota T.   +5 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Risk of all-cause death and pancreatic events following GLP-1 RA initiation in people with obesity or type 2 diabetes: observations from a federated research network. [PDF]

Cardiovasc Diabetol
Tartaglia E, Bucci T, Rossi M, Rigutini AG, Askarinejad A, Alam U, Nabrdalik K, Boriani G, Lip GYH.   +8 more
europepmc   +1 more source

Balance ability and all-cause death in middle-aged and older adults: A prospective cohort study. [PDF]

Front Public Health, 2022
Xie K, Han X, Hu X.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Association of Lipid Profile With Cardiovascular Diseases and All-Cause Death: A 2-Decade Follow-Up of the Tehran Lipid and Glucose Study. [PDF]

J Am Heart Assoc
Ramezankhani A, Azizi F, Hadaegh F.
europepmc   +1 more source

Association of low diastolic blood pressure with all-cause death among US adults with normal systolic blood pressure. [PDF]

J Clin Hypertens (Greenwich), 2023
Wang Z, Yu C, Cao X, He Y, Ju W.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Association of unsaturated fatty acid intake with risk of all-cause death in patients with osteoarthritis. [PDF]

Front Nutr
Li T, Tang Z, Li S, Jiang W, Lu M.
europepmc   +1 more source

Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all-cause death in heart failure patients. [PDF]

Nurs Open, 2023
Zhao L, Zhao X, Zhuang X, Zhai M, Wang Y, Huang Y, Zhou Q, Tian P, Liang L, Huang B, Huang L, Feng J, Zhang Y, Zhang J.   +13 more
europepmc   +1 more source